Highlights from the 2019 International Aspirin Foundation Scientific Conference, Rome, 28 June 2019: benefits and risks of antithrombotic therapy for cardiovascular disease prevention.
anticoagulant
antiplatelet
antithrombotic
aspirin
benefit
cardiovascular disease (CVD)
colorectal cancer (CRC)
diabetes mellitus (DM)
gastroprotectant agents
optimizing aspirin dose
precision medicine
primary prevention
risk
secondary prevention
targeting
upper gastrointestinal (GI) bleeding
Journal
Ecancermedicalscience
ISSN: 1754-6605
Titre abrégé: Ecancermedicalscience
Pays: England
ID NLM: 101392236
Informations de publication
Date de publication:
2020
2020
Historique:
received:
26
09
2019
entrez:
11
3
2020
pubmed:
11
3
2020
medline:
11
3
2020
Statut:
epublish
Résumé
At the 2019 International Aspirin Foundation Scientific Conference 'Benefits and Risks of Antithrombotic Therapy for Cardiovascular Disease Prevention', held in Rome, Italy, international experts sought to discuss and debate the optimal antithrombotic strategy for the secondary prevention of cardiovascular disease (CVD) and to seek agreement around dosing and target populations for aspirin use in primary disease prevention. Getting the best evidence to support real-life decisions in the clinic can be complex, and individualising management in order to balance both the risks and benefits of different disease prevention strategies appears to be the best approach. It is hoped that future decision-making tools and biomarkers will help direct treatments at those most likely to benefit.
Identifiants
pubmed: 32153653
doi: 10.3332/ecancer.2020.998
pii: can-14-998
pmc: PMC7032943
doi:
Types de publication
Journal Article
Langues
eng
Pagination
998Informations de copyright
© the authors; licensee ecancermedicalscience.
Déclaration de conflit d'intérêts
Professor Marco Cattaneo: Research support/P.I: Eli Lilly, Daiichi Sankyo, Astra Zeneca, Evolva. Honoraria: Eli Lilly, Daiichi Sankyo, Astra Zeneca, MSD, Evolva. Scientific Advisory Board: Eli Lilly, Daiichi Sankyo, Astra Zeneca, Evolva, The Medicines Company, MSD. Professor Lina Badimon: Consultant and speaker fees from Sanofi, AstraZeneca, Amgem. Grant support for investigator-initiated research from: European Commission, FP6 and FP7 programmes, National Funding Agencies, AstraZeneca. Professor Giancarlo Agnelli: Speaker bureaux: Bristol-Myers Squibb/Pfizer, Bayer Healthcare. Advisory boards: Bristol-Myers Squibb/Pfizer, Daiichi Sankyo, Bayer Healthcare. Professor Andrew Chan: Consultant for Pfizer Inc, Bayer Pharma AG, Janssen. Grants for investigator-initiated research National Institute of Health, National Cancer Institute, Crohn’s and Colitis Foundation, Bayer AG. 2019 American Association for Cancer Research AACR-Waun Ki Hong Award. Professor Angel Lanas: none. Professor Bianca Rocca: Institutional research grants, research grants from the Italian Medicines Agency (AIFA), consultancy from Bayer AG. Professor Peter Rothwell: Consultant and speaker fees from Bayer AG. Professor Paola Patrignani: Grant Associazione Italiana per la Ricerca sul Cancro (AIRC, IG-12111), Aspirin for Cancer Prevention Group (AsCaP), Bayer for the PK/PD studies with EC-ASA, Fellowship to Dr Angela Sacco by SIF-Merck 2017. Professor Ruth Langley: Honorarium Bayer, clinical trial drug supplies for an academic study. Dr Gemma Vilahur: Speaker fees from AstraZeneca, research grants from National Funding Agencies. Professor Francesco Consentino: Research grants: Swedish Research Council, Swedish Heart and Lung foundation, Karolinska Institutet, European Foundation for the Study of Diabetes, Swedish Diabetes Foundation, King Gustav V and Queen Victoria Foundation. Advisory board/speaker: AstraZeneca, Boehringer Ingelheim, Bristol Myers Squibb, Eli Lilly, Merck Sharp and Dohme, Mundipharma, Novo Nordisk, Pfizer.
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