Cobalt-Directed Assembly of Antibodies onto Metal-Phenolic Networks for Enhanced Particle Targeting.

Animals Antibodies, Immobilized / chemistry Cell Line Cobalt / chemistry Cross-Linking Reagents / chemistry Fluorescent Dyes / chemistry Gold / chemistry Humans Immunoglobulin G / chemistry Metal Nanoparticles / chemistry Molecular Dynamics Simulation Tannins / chemistry
antibodies metal−phenolic networks molecular modeling self-assembly targeting

Journal

Nano letters
ISSN: 1530-6992
Titre abrégé: Nano Lett
Pays: United States
ID NLM: 101088070

Informations de publication

Date de publication:
08 04 2020
Historique:
pubmed: 11 3 2020
medline: 26 1 2021
entrez: 11 3 2020
Statut: ppublish

Résumé

The orientation-specific immobilization of antibodies onto nanoparticles, to preserve antibody-antigen recognition, is a key challenge in developing targeted nanomedicines. Herein, we report the targeting ability of metal-phenolic network (MPN)-coated gold nanoparticles with surface-physisorbed antibodies against respective antigens. The MPN coatings were self-assembled from metal ions (Fe

Identifiants

DOI: 10.1021/acs.nanolett.0c00295 PMID: 32155075
pubmed: 32155075
doi: 10.1021/acs.nanolett.0c00295
doi:

Substances chimiques

Antibodies, Immobilized 0
Cross-Linking Reagents 0
Fluorescent Dyes 0
Immunoglobulin G 0
Tannins 0
Cobalt 3G0H8C9362
Gold 7440-57-5

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

2660-2666

Auteurs

Wenjie Zhang (W)

ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, and the Department of Chemical Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia.

Quinn A Besford (QA)

ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, and the Department of Chemical Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia.

Andrew J Christofferson (AJ)

School of Engineering, RMIT University, GPO Box 2476, Melbourne, Victoria 3001, Australia.
ORCID: 0000-0003-0904-6630

Patrick Charchar (P)

School of Engineering, RMIT University, GPO Box 2476, Melbourne, Victoria 3001, Australia.
ORCID: 0000-0002-9201-4711

Joseph J Richardson (JJ)

ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, and the Department of Chemical Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia.

Aaron Elbourne (A)

Nanobiotechnology Laboratory, School of Science, RMIT University, Melbourne Victoria 3001, Australia.
ORCID: 0000-0002-4472-4372

Kristian Kempe (K)

ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, and Drug Delivery, Disposition and Dynamics, Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria 3052, Australia.
ORCID: 0000-0002-0136-9403

Christoph E Hagemeyer (CE)

NanoBiotechnology Laboratory, Australian Centre for Blood Diseases, Monash University, Melbourne, Victoria 3004, Australia.

Matthew R Field (MR)

RMIT Microscopy & Microanalysis Facility, RMIT University, Melbourne, Victoria 3001, Australia.

Chris F McConville (CF)

College of Science, Engineering and Health, RMIT University, GPO Box 2476, Melbourne, Victoria 3001, Australia.

Irene Yarovsky (I)

School of Engineering, RMIT University, GPO Box 2476, Melbourne, Victoria 3001, Australia.
ORCID: 0000-0002-4033-5150

Frank Caruso (F)

ARC Centre of Excellence in Convergent Bio-Nano Science and Technology, and the Department of Chemical Engineering, The University of Melbourne, Parkville, Victoria 3010, Australia.
ORCID: 0000-0002-0197-497X

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Cobalt-Directed Assembly of Antibodies onto...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines immobilisées › Anticorps immobilisés › Cobalt-Directed Assembly of Antibodies onto...
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › Cobalt-Directed Assembly of Antibodies onto...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Cobalt › Cobalt-Directed Assembly of Antibodies onto...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Réactifs réticulants › Cobalt-Directed Assembly of Antibodies onto...
questionsmedicales.fr › Actions chimiques et utilisations › Utilisations spécialisées de produits chimiques › Produits chimiques de laboratoire › Indicateurs et réactifs › Luminescents › Colorants fluorescents › Cobalt-Directed Assembly of Antibodies onto...
questionsmedicales.fr › Produits chimiques inorganiques › Métaux › Métaux lourds › Or › Cobalt-Directed Assembly of Antibodies onto...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Cobalt-Directed Assembly of Antibodies onto...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Isotypes des immunoglobulines › Immunoglobuline G › Cobalt-Directed Assembly of Antibodies onto...
questionsmedicales.fr › Technologie, industrie et agriculture › Produits manufacturés › Nanostructures › Nanoparticules › Nanoparticules métalliques › Cobalt-Directed Assembly of Antibodies onto...
questionsmedicales.fr › Sciences de l'information › Méthodologies informatiques › Simulation numérique › Simulation de dynamique moléculaire › Cobalt-Directed Assembly of Antibodies onto...
questionsmedicales.fr › Structures macromoléculaires › Tanins › Cobalt-Directed Assembly of Antibodies onto...