Impaired integrin α


Journal

Aging cell
ISSN: 1474-9726
Titre abrégé: Aging Cell
Pays: England
ID NLM: 101130839

Informations de publication

Date de publication:
04 2020
Historique:
received: 17 09 2019
revised: 20 01 2020
accepted: 16 02 2020
pubmed: 12 3 2020
medline: 21 5 2021
entrez: 12 3 2020
Statut: ppublish

Résumé

Hepatic blood flow and sinusoidal endothelial fenestration decrease during aging. Consequently, fluid mechanical forces are reduced in the space of Disse where hepatic stellate cells (HSC) have their niche. We provide evidence that integrin α

Identifiants

pubmed: 32157808
doi: 10.1111/acel.13131
pmc: PMC7189994
doi:

Substances chimiques

Integrin alpha5beta1 0
Hepatocyte Growth Factor 67256-21-7

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

e13131

Informations de copyright

© 2020 The Authors. Aging Cell published by Anatomical Society and John Wiley & Sons Ltd.

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Auteurs

Friederike Rohn (F)

Clinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, Düsseldorf, Germany.

Claus Kordes (C)

Clinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, Düsseldorf, Germany.

Tobias Buschmann (T)

Clinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, Düsseldorf, Germany.

Doreen Reichert (D)

Clinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, Düsseldorf, Germany.

Marianne Wammers (M)

Clinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, Düsseldorf, Germany.

Gereon Poschmann (G)

Institute for Molecular Medicine, Heinrich Heine University, Düsseldorf, Germany.

Kai Stühler (K)

Institute for Molecular Medicine, Heinrich Heine University, Düsseldorf, Germany.
Molecular Proteomics Laboratory, BMFZ, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.

Amelie S Benk (AS)

Department of Cellular Biophysics, Max-Planck-Institute for Medical Research, Heidelberg, Germany.
Department of Biophysical Chemistry, University of Heidelberg, Heidelberg, Germany.

Fania Geiger (F)

Department of Cellular Biophysics, Max-Planck-Institute for Medical Research, Heidelberg, Germany.
Department of Biophysical Chemistry, University of Heidelberg, Heidelberg, Germany.

Joachim P Spatz (JP)

Department of Cellular Biophysics, Max-Planck-Institute for Medical Research, Heidelberg, Germany.
Department of Biophysical Chemistry, University of Heidelberg, Heidelberg, Germany.

Dieter Häussinger (D)

Clinic of Gastroenterology, Hepatology and Infectious Diseases, Heinrich Heine University, Düsseldorf, Germany.

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Classifications MeSH