acute coronary syndrome
atrial fibrillation
clopidogrel
polymorphism
rivaroxaban
Journal
Pharmacogenomics and personalized medicine
ISSN: 1178-7066
Titre abrégé: Pharmgenomics Pers Med
Pays: New Zealand
ID NLM: 101514107
Informations de publication
Date de publication:
2020
2020
Historique:
received:
16
10
2019
accepted:
03
01
2020
entrez:
12
3
2020
pubmed:
12
3
2020
medline:
12
3
2020
Statut:
epublish
Résumé
The aim of this study is to assess the influence of gene In the multicenter prospective registry study of the efficacy and safety of a combined antithrombotic therapy 103 patients with non-valvular atrial fibrillation both undergoing or not a percutaneous coronary intervention were enrolled. The trial assessed the primary outcomes (major bleeding, in-hospital death, cardiovascular death, stroke\transient ischaemic attack, death/renal insufficiency) and secondary outcomes (platelet reactivity units (PRU), rivaroxaban concentration). For none of the clinical outcomes when combined with other covariates, the carriership of polymorphisms In situations of double or triple antithrombotic rivaroxaban and clopidogrel therapy among patients with atrial fibrillation and acute coronary syndrome, the genetic factors associated with bleeding complications risk (
Identifiants
pubmed: 32158254
doi: 10.2147/PGPM.S234910
pii: 234910
pmc: PMC6986167
doi:
Types de publication
Journal Article
Langues
eng
Pagination
29-37Informations de copyright
© 2020 Sychev et al.
Déclaration de conflit d'intérêts
Dmitriy Ivashchenko reports grants from Russian Science Foundation and RFBR, outside the submitted work. The other authors report no conflicts of interest in this work.
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