Covalent Modification of the Flavin in Proline Dehydrogenase by Thiazolidine-2-Carboxylate.
Bacterial Proteins
/ antagonists & inhibitors
Crystallography, X-Ray
Dinitrocresols
/ chemistry
Enzyme Inhibitors
/ chemistry
Kinetics
Models, Chemical
Oxidation-Reduction
Proline
/ analogs & derivatives
Proline Oxidase
/ antagonists & inhibitors
Sinorhizobium meliloti
/ enzymology
Thiazolidines
/ chemistry
Journal
ACS chemical biology
ISSN: 1554-8937
Titre abrégé: ACS Chem Biol
Pays: United States
ID NLM: 101282906
Informations de publication
Date de publication:
17 04 2020
17 04 2020
Historique:
pubmed:
12
3
2020
medline:
23
1
2021
entrez:
12
3
2020
Statut:
ppublish
Résumé
Proline dehydrogenase (PRODH) catalyzes the first step of proline catabolism, the FAD-dependent 2-electron oxidation of l-proline to Δ
Identifiants
pubmed: 32159324
doi: 10.1021/acschembio.9b00935
pmc: PMC7166166
mid: NIHMS1577935
doi:
Substances chimiques
Bacterial Proteins
0
Dinitrocresols
0
Enzyme Inhibitors
0
Thiazolidines
0
4,6-dinitro-o-cresol
1604ZJR09T
thiazolidine-2-carboxylic acid
16310-13-7
Proline
9DLQ4CIU6V
Proline Oxidase
EC 1.5.3.-
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Langues
eng
Sous-ensembles de citation
IM
Pagination
936-944Subventions
Organisme : NCRR NIH HHS
ID : S10 RR029205
Pays : United States
Organisme : NIGMS NIH HHS
ID : P30 GM124169
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM065546
Pays : United States
Organisme : NIGMS NIH HHS
ID : P30 GM124165
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM061068
Pays : United States
Références
Biochemistry. 2007 Jan 16;46(2):483-91
pubmed: 17209558
Acta Crystallogr D Biol Crystallogr. 2009 Oct;65(Pt 10):1074-80
pubmed: 19770504
Proc Natl Acad Sci U S A. 1979 Jun;76(6):2625-9
pubmed: 37501
Mol Cancer Res. 2015 Oct;13(10):1408-20
pubmed: 26082174
J Biol Chem. 2016 Nov 11;291(46):24065-24075
pubmed: 27679491
Acta Crystallogr D Biol Crystallogr. 2010 Apr;66(Pt 4):486-501
pubmed: 20383002
Nature. 1997 Sep 18;389(6648):300-5
pubmed: 9305847
Acta Crystallogr D Biol Crystallogr. 2013 Jul;69(Pt 7):1204-14
pubmed: 23793146
J Hum Genet. 2004;49(3):134-140
pubmed: 14986171
J Org Chem. 2019 Feb 1;84(3):1218-1227
pubmed: 30605336
Biochemistry. 2000 Jun 13;39(23):6969-78
pubmed: 10841779
J Biol Chem. 1982 Feb 10;257(3):1166-71
pubmed: 6120164
Proc Natl Acad Sci U S A. 2014 Mar 4;111(9):3389-94
pubmed: 24550478
Nat Commun. 2017 May 11;8:15267
pubmed: 28492237
Nat Commun. 2014;5:3128
pubmed: 24451681
PLoS One. 2013 Jul 08;8(7):e69152
pubmed: 23861960
Molecules. 2017 Dec 23;23(1):
pubmed: 29295473
Acta Crystallogr D Biol Crystallogr. 2010 Jan;66(Pt 1):12-21
pubmed: 20057044
Antioxid Redox Signal. 2019 Feb 1;30(4):650-673
pubmed: 28990412
Acta Crystallogr D Biol Crystallogr. 2012 Apr;68(Pt 4):352-67
pubmed: 22505256
Structure. 2017 Dec 5;25(12):1916-1927
pubmed: 29174494
Mol Cancer Ther. 2019 Aug;18(8):1374-1385
pubmed: 31189611
FEBS J. 2017 Sep;284(18):3029-3049
pubmed: 28710792
Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):125-32
pubmed: 20124692
Arch Biochem Biophys. 2017 Oct 15;632:142-157
pubmed: 28712849
Biochemistry. 2010 Jan 26;49(3):560-9
pubmed: 19994913
Biochemistry. 2008 May 20;47(20):5573-80
pubmed: 18426222
Biochemistry. 2018 Jun 26;57(25):3433-3444
pubmed: 29648801
J Biol Chem. 2014 Feb 7;289(6):3639-51
pubmed: 24352662
Biochemistry. 2012 Jan 10;51(1):511-20
pubmed: 22148640
Drug Discov Today. 2014 Dec;19(12):1953-63
pubmed: 25256776