Safety and Effectiveness of Neuro-thrombectomy on Single compared to Biplane Angiography Systems.


Journal

Scientific reports
ISSN: 2045-2322
Titre abrégé: Sci Rep
Pays: England
ID NLM: 101563288

Informations de publication

Date de publication:
11 03 2020
Historique:
received: 26 09 2019
accepted: 14 02 2020
entrez: 13 3 2020
pubmed: 13 3 2020
medline: 21 11 2020
Statut: epublish

Résumé

An increasing number of centers not necessarily equipped with biplane (BP) angiosuites are performing mechanical thrombectomy (MT) in acute ischemic stroke patients. We assessed whether MT performed on single-plane (SP) is equivalent in terms of safety, effectiveness, radiation and contrast agent exposure. Consecutive patients treated by MT in four high volume centers between January 2014 and May 2017 were included. Demographic and MT characteristics were assessed and compared between SP and BP. Of 906 patients treated by MT, 576 (64%) were handled on a BP system. After multivariate analysis, contrast load and fluoroscopy duration were significantly lower in the BP group [100vs200mL, relative effect 0.85 (CI: 0.79-0.92), p = 0.0002; 22 vs 27 min, relative effect 0.84 (CI: 0.76-0.93), p = 0.0008, respectively]. There was no difference in recanalization (modified Thrombolysis-In-Cerebral-Infarction 2b-3), good clinical outcome (modified Rankin Scale 0-2), complications rates, procedure duration or radiation exposure. A three-vessel diagnostic angiogram performed prior to MT led to a significant increase in procedure duration (15% increase, p = 0.05), radiation exposure (33% increase, p < 0.0001) and contrast load (125% increase, p < 0.0001). Mechanical neuro-thrombectomy seems equally safe and effective on a single or biplane angiography system despite increased contrast load and fluoroscopy duration on the former.

Identifiants

pubmed: 32161286
doi: 10.1038/s41598-020-60851-4
pii: 10.1038/s41598-020-60851-4
pmc: PMC7066129
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

4470

Investigateurs

Eike Piechowiak (E)
Pasquale Mordasini (P)
Felix Zibold (F)
Celina Ducroux (C)
Fabrice Bonneville (F)
Jean Darcourt (J)
Ivan Vukasinovic (I)
Anne Christine Januel (AC)
Sylvie Monfraix (S)
Caterina Michelozzi (C)
Philippe Tall (P)
Mikael Mazighi (M)
Jean-Philippe Desilles (JP)
Gabriele Ciccio (G)
Stanislas Smajda (S)
Hocine Redjem (H)
Benjamin Maier (B)
Blake W Martin (BW)
Elisa Guenego (E)
Fanny Carbillet (F)

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Auteurs

Adrien Guenego (A)

Interventional and Diagnostic Neuroradiology Department, Toulouse University Hospital, Toulouse, France. adrienguenego@gmail.com.

Pascal J Mosimann (PJ)

Interventional and diagnostic Neuroradiology, Bern, Switzerland.

Max Wintermark (M)

Interventional and Diagnostic Neuroradiology, Stanford Medical Center, California, USA.

Jeremy J Heit (JJ)

Interventional and Diagnostic Neuroradiology, Stanford Medical Center, California, USA.

Kevin Zuber (K)

Statistics department, Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.

Tomas Dobrocky (T)

Interventional and diagnostic Neuroradiology, Bern, Switzerland.

Jean Albert Lotterie (JA)

Stereotaxic Neurosurgery Department, Toulouse University Hospital, Toulouse, France.

Patrick Nicholson (P)

Interventional and Diagnostic Neuroradiology, Toronto Hospital, Toronto, Canada.

David G Marcellus (DG)

Interventional and Diagnostic Neuroradiology, Stanford Medical Center, California, USA.

Jean Marc Olivot (JM)

Vascular Neurology, Stroke Department, Toulouse University Hospital, Toulouse, France.

Nestor Gonzalez (N)

Neurosurgery and Interventional Neuroradiology Department, Cedars Sinai Hospital, Los Angeles, USA.

Raphaël Blanc (R)

Interventional Neuroradiology, Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.

Vitor Mendes Pereira (VM)

Interventional and Diagnostic Neuroradiology, Toronto Hospital, Toronto, Canada.

Jan Gralla (J)

Interventional and diagnostic Neuroradiology, Bern, Switzerland.

Johannes Kaesmacher (J)

Interventional and diagnostic Neuroradiology, Bern, Switzerland.

Robert Fahed (R)

Interventional Neuroradiology, Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.

Michel Piotin (M)

Interventional Neuroradiology, Fondation Ophtalmologique Adolphe de Rothschild, Paris, France.

Christophe Cognard (C)

Interventional and Diagnostic Neuroradiology Department, Toulouse University Hospital, Toulouse, France.

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