Is There a Role for Levo-Thyroxine for the Treatment of Arterial Erectile Dysfunction? The Clinical Relevance of the Mean Platelet Volume.

erectile dysfunction levo-thyroxine mean platelet value mean platelet volume (MPV). peak systolic velocity subclinical hypothyroidism

Journal

Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588

Informations de publication

Date de publication:
10 Mar 2020
Historique:
received: 19 02 2020
revised: 06 03 2020
accepted: 09 03 2020
entrez: 14 3 2020
pubmed: 14 3 2020
medline: 14 3 2020
Statut: epublish

Résumé

Arterial erectile dysfunction (ED) is an early sign of vascular damage. Rare evidence has been published so far as to whether subclinical hypothyroidism (SCH) affects arterial erectile function. Therefore, the objective of this study was to fill this gap. Patients with arterial ED and SCH were consecutive enrolled and randomly divided into Group A ( Group A and B did not differ for age (61.2 ± 4.8 vs. 60.3 ± 5.6 years), body-mass index (28.7 ± 2.5 vs. 28.3 ± 2.6 Kg/m Lt4 therapy is associated with an improvement of the erectile function at the vascular level, a decrease in MPV and total cholesterol. LT4 therapy should be considered in patients with arterial ED and SCH.

Sections du résumé

BACKGROUND BACKGROUND
Arterial erectile dysfunction (ED) is an early sign of vascular damage. Rare evidence has been published so far as to whether subclinical hypothyroidism (SCH) affects arterial erectile function. Therefore, the objective of this study was to fill this gap.
METHODS METHODS
Patients with arterial ED and SCH were consecutive enrolled and randomly divided into Group A (
RESULTS RESULTS
Group A and B did not differ for age (61.2 ± 4.8 vs. 60.3 ± 5.6 years), body-mass index (28.7 ± 2.5 vs. 28.3 ± 2.6 Kg/m
CONCLUSIONS CONCLUSIONS
Lt4 therapy is associated with an improvement of the erectile function at the vascular level, a decrease in MPV and total cholesterol. LT4 therapy should be considered in patients with arterial ED and SCH.

Identifiants

pubmed: 32164208
pii: jcm9030742
doi: 10.3390/jcm9030742
pmc: PMC7141360
pii:
doi:

Types de publication

Journal Article

Langues

eng

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Auteurs

Rossella Cannarella (R)

Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.

Aldo E Calogero (AE)

Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.

Antonio Aversa (A)

Department of Experimental and Clinical Medicine, "Magna Graecia" University, 88100 Catanzaro, Italy.

Rosita A Condorelli (RA)

Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.

Sandro La Vignera (S)

Department of Clinical and Experimental Medicine, University of Catania, 95123 Catania, Italy.

Classifications MeSH