A Carotid Doppler Patch Accurately Tracks Stroke Volume Changes During a Preload-Modifying Maneuver in Healthy Volunteers.

Detecting instantaneous stroke volume change in response to altered cardiac preload is the physiologic foundation for determining preload responsiveness. Proof-of-concept physiology study. Research simulation laboratory. Twelve healthy volunteers. A wireless continuous wave Doppler ultrasound patch was used to measure carotid velocity time integral and carotid corrected flow time during a squat maneuver. The Doppler patch measurements were compared with simultaneous stroke volume measurements obtained from a noninvasive cardiac output monitor. From stand to squat, stroke volume increased by 24% while carotid velocity time integral and carotid corrected flow time increased by 32% and 9%, respectively. From squat to stand, stroke volume decreased by 13%, while carotid velocity time integral and carotid corrected flow time decreased by 24% and 10%, respectively. Both changes in carotid velocity time integral and corrected flow time were closely correlated with changes in stroke volume ( In healthy volunteers, both carotid velocity time integral and carotid corrected flow time measured by a wireless Doppler patch were useful to track changes in stroke volume induced by a preload-modifying maneuver with high sensitivity and specificity.

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Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of the Society of Critical Care Medicine.

Déclaration de conflit d'intérêts

Drs. Kenny, Andrew M. Eibl, Parrotta, Long, and Joseph K. Eibl are working with Flosonics, a start-up developing a commercial version of the Doppler patch. Dr. Michard is the founder and managing director of MiCo, a Swiss consulting firm. MiCo does not sell any medical products, and Dr. Michard does not own shares nor receive royalties from any MedTech company. Dr. Barjaktarevic has disclosed that he does not have any potential conflicts of interest.