Ablation for hepatocellular carcinoma: beyond the standard indications.


Journal

Medical oncology (Northwood, London, England)
ISSN: 1559-131X
Titre abrégé: Med Oncol
Pays: United States
ID NLM: 9435512

Informations de publication

Date de publication:
12 Mar 2020
Historique:
received: 12 12 2019
accepted: 20 02 2020
entrez: 14 3 2020
pubmed: 14 3 2020
medline: 21 10 2020
Statut: epublish

Résumé

Hepatocellular carcinoma (HCC), the most common primary liver neoplasia, represents the fifth most common malignant disease in men. Percutaneous ablation treatment is recommended among the treatments suggested for HCC patients in the very early/early stage. In the last decade, very important results in terms of survival benefits have been obtained with local ablative therapies, also outside the standard indications, thanks to many technical innovations. In particular, important results of ablation as a safe and effective technique have been obtained in the treatment of intermediate- or advanced-stage patients with HCC, and in the treatment of unfavourable tumour locations. Moreover, awareness is growing regarding the necessity of overcoming the rigidity of traditional guidelines in the treatment of HCC due to the complexity of patients with HCC, focusing on Precision Medicine. In this context, it is important to know the standard and non-standard indications of ablation in the treatment of HCC in order to offer the best therapeutic option tailored for each patient. The aim of this study was to analyse the possible clinical applications of ablative therapies for HCC patients, beyond the traditional indications recommended in the most widespread clinical practice guidelines for the management of HCC.

Identifiants

pubmed: 32166482
doi: 10.1007/s12032-020-01348-y
pii: 10.1007/s12032-020-01348-y
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

23

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Auteurs

Matteo Renzulli (M)

Radiology Unit, Department of Experimental, Diagnostic and Speciality Medicine, Sant'Orsola Hospital, University of Bologna, Via Albertoni 15, 40138, Bologna, Italy. matteo.renzulli@aosp.bo.it.

Francesco Tovoli (F)

Unit of Internal Medicine, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

Alfredo Clemente (A)

Radiology and Radiotherapy Unit, Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

Anna Maria Ierardi (AM)

Diagnostic and Interventional Radiology Department, ASST Santi Paolo e Carlo, San Paolo Hospital, University of Milan, Milan, Italy.

Irene Pettinari (I)

Radiology Unit, Department of Experimental, Diagnostic and Speciality Medicine, Sant'Orsola Hospital, University of Bologna, Via Albertoni 15, 40138, Bologna, Italy.

Giuliano Peta (G)

Radiology Unit, Department of Experimental, Diagnostic and Speciality Medicine, Sant'Orsola Hospital, University of Bologna, Via Albertoni 15, 40138, Bologna, Italy.

Giovanni Marasco (G)

Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

Davide Festi (D)

Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

Fabio Piscaglia (F)

Unit of Internal Medicine, Department of Medical and Surgical Sciences, University of Bologna, Bologna, Italy.

Salvatore Cappabianca (S)

Radiology and Radiotherapy Unit, Department of Precision Medicine, University of Campania "L. Vanvitelli", Naples, Italy.

Gianpaolo Carrafiello (G)

Diagnostic and Interventional Radiology Department, ASST Santi Paolo e Carlo, San Paolo Hospital, University of Milan, Milan, Italy.

Rita Golfieri (R)

Radiology Unit, Department of Experimental, Diagnostic and Speciality Medicine, Sant'Orsola Hospital, University of Bologna, Via Albertoni 15, 40138, Bologna, Italy.

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