Switchable Lipid Provides pH-Sensitive Properties to Lipid and Hybrid Polymer/Lipid Membranes.

giant hybrid polymer/lipid vesicles giant unilamellar vesicles hybrid polymer/lipid membrane pH-sensitive liposomes responsive vesicles switchable lipid

Journal

Polymers
ISSN: 2073-4360
Titre abrégé: Polymers (Basel)
Pays: Switzerland
ID NLM: 101545357

Informations de publication

Date de publication:
11 Mar 2020
Historique:
received: 13 02 2020
revised: 02 03 2020
accepted: 06 03 2020
entrez: 15 3 2020
pubmed: 15 3 2020
medline: 15 3 2020
Statut: epublish

Résumé

Blending amphiphilic copolymers and lipids constitutes a novel approach to combine the advantages of polymersomes and liposomes into a new single hybrid membrane. Efforts have been made to design stimuli-responsive vesicles, in which the membrane's dynamic is modulated by specific triggers. In this investigation, we proposed the design of pH-responsive hybrid vesicles formulated with poly(dimethylsiloxane)-

Identifiants

pubmed: 32168824
pii: polym12030637
doi: 10.3390/polym12030637
pmc: PMC7183064
pii:
doi:

Types de publication

Journal Article

Langues

eng

Subventions

Organisme : Mitacs
ID : IT12887

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

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Auteurs

Victor Passos Gibson (V)

Gene Delivery Laboratory, Faculty of pharmacy, University of Montréal, Montréal, QC H3C 3J7, Canada.

Martin Fauquignon (M)

Laboratoire de Chimie des Polymères Organiques, LCPO, Université de Bordeaux, CNRS, Bordeaux INP, UMR 5629, Avenue Pey Berland, F-33600 Pessac, France.

Emmanuel Ibarboure (E)

Laboratoire de Chimie des Polymères Organiques, LCPO, Université de Bordeaux, CNRS, Bordeaux INP, UMR 5629, Avenue Pey Berland, F-33600 Pessac, France.

Jeanne Leblond Chain (J)

Gene Delivery Laboratory, Faculty of pharmacy, University of Montréal, Montréal, QC H3C 3J7, Canada.
ARNA Laboratory, INSERM U1212, CNRS UMR 5320, University of Bordeaux, Faculty of Pharmacy, F-33016 Bordeaux, France.

Jean-François Le Meins (JF)

Laboratoire de Chimie des Polymères Organiques, LCPO, Université de Bordeaux, CNRS, Bordeaux INP, UMR 5629, Avenue Pey Berland, F-33600 Pessac, France.

Classifications MeSH