Regional Patterns and Association Between Obesity and Hypertension in Africa: Evidence From the H3Africa CHAIR Study.


Journal

Hypertension (Dallas, Tex. : 1979)
ISSN: 1524-4563
Titre abrégé: Hypertension
Pays: United States
ID NLM: 7906255

Informations de publication

Date de publication:
05 2020
Historique:
pubmed: 17 3 2020
medline: 7 4 2021
entrez: 17 3 2020
Statut: ppublish

Résumé

Hypertension and obesity are the most important modifiable risk factors for cardiovascular diseases, but their association is not well characterized in Africa. We investigated regional patterns and association of obesity with hypertension among 30 044 continental Africans. We harmonized data on hypertension (defined as previous diagnosis/use of antihypertensive drugs or blood pressure [BP]≥140/90 mmHg/BP≥130/80 mmHg) and obesity from 30 044 individuals in the Cardiovascular H3Africa Innovation Resource across 13 African countries. We analyzed data from population-based controls and the Entire Harmonized Dataset. Age-adjusted and crude proportions of hypertension were compared regionally, across sex, and between hypertension definitions. Logit generalized estimating equation was used to determine the independent association of obesity with hypertension (

Identifiants

pubmed: 32172619
doi: 10.1161/HYPERTENSIONAHA.119.14147
pmc: PMC7176339
doi:

Substances chimiques

Antihypertensive Agents 0

Types de publication

Comparative Study Journal Article Research Support, N.I.H., Extramural Research Support, N.I.H., Intramural Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1167-1178

Subventions

Organisme : NIDDK NIH HHS
ID : U54 DK116913
Pays : United States
Organisme : NHGRI NIH HHS
ID : U54 HG006938
Pays : United States
Organisme : NHGRI NIH HHS
ID : U54 HG006939
Pays : United States
Organisme : NHGRI NIH HHS
ID : U54 HG007479
Pays : United States
Organisme : NINDS NIH HHS
ID : R01 NS107900
Pays : United States
Organisme : NHGRI NIH HHS
ID : U01 HG010273
Pays : United States
Organisme : NHGRI NIH HHS
ID : U54 HG006947
Pays : United States
Organisme : Wellcome Trust
ID : 099313/Z/12/Z
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 099313/B/12/Z
Pays : United Kingdom

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Auteurs

Onoja M Akpa (OM)

From the Center for Genomic and Precision Medicine, College of Medicine, (O.M.A., B.S., R.A., M.O.O.), University of Ibadan, Ibadan, Nigeria.
Department of Epidemiology and Medical Statistics, College of Medicine (O.M.A.), University of Ibadan, Ibadan, Nigeria.
Institute of Cardiovascular Diseases, College of Medicine (O.M.A.), University of Ibadan, Ibadan, Nigeria.
Sydney Brenner Institute for Molecular Bioscience and Division of Human Genetics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (O.M.A., F. Made, S.A.A., M.R.).

Felix Made (F)

The Epidemiology and Surveillance Section, National Institute for Occupational Health, National Health Laboratory Services, Gauteng Region, South Africa (F. Made).
Sydney Brenner Institute for Molecular Bioscience and Division of Human Genetics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (O.M.A., F. Made, S.A.A., M.R.).

Akinlolu Ojo (A)

Clinical research and global health initiatives, University of Arizona Health Sciences (A.O.).

Bruce Ovbiagele (B)

Department of Neurology, University of California, San Francisco CA, USA (B.O.).

Dwomoa Adu (D)

School of Medicine and Dentistry, University of Ghana, Accra, Ghana (D.A.).

Ayesha A Motala (AA)

Department of Diabetes and Endocrinology, Nelson R. Mandela School of Medicine, University of KwaZulu-Natal, Durban, South Africa (A.A.M.).

Bongani M Mayosi (BM)

Department of Medicine, Groote Schuur Hospital (B.M.M.), University of Cape Town, South Africa.

Sally N Adebamowo (SN)

Department of Epidemiology and Public Health, Greenebaum Comprehensive Cancer Center, University of Maryland School of Medicine, Baltimore, MD, USA (S.N.A.).

Mark E Engel (ME)

Division of Cardiology, Department of Medicine (M.E.E., C.C.), University of Cape Town, South Africa.

Bamidele Tayo (B)

Department of Preventive Medicine and Epidemiology, Loyola University Chicago Stritch School of Medicine, Maywood, IL (B.T.).

Charles Rotimi (C)

Center for Research on Genomics and Global Health, NHGRI, NIH, Bethesda, MD, USA (C.R.).

Babatunde Salako (B)

From the Center for Genomic and Precision Medicine, College of Medicine, (O.M.A., B.S., R.A., M.O.O.), University of Ibadan, Ibadan, Nigeria.

Rufus Akinyemi (R)

From the Center for Genomic and Precision Medicine, College of Medicine, (O.M.A., B.S., R.A., M.O.O.), University of Ibadan, Ibadan, Nigeria.

Mulugeta Gebregziabher (M)

Department of Public Health Sciences, Medical University of South Carolina, Charleston SC, USA (M.G.).

Fred Sarfo (F)

Kwame Nkrumah University of Science and Technology, Kumasi, Ghana (F.S.).

Kolawole Wahab (K)

Department of Medicine, University of Ilorin, Nigeria (K. Wahab).

Godfred Agongo (G)

Navrongo Health Research Centre, Ghana (G. Agongo, E.A.N.).

Marianne Alberts (M)

Department of Pathology and Medical Science, School of Health Care Sciences, Faculty of Health Sciences, University of Limpopo, Polokwane, South Africa (M.A., F. Mashinya).

Stuart A Ali (SA)

Sydney Brenner Institute for Molecular Bioscience and Division of Human Genetics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (O.M.A., F. Made, S.A.A., M.R.).

Gershim Asiki (G)

African Population and Health Research Center, Nairobi, Kenya (G. Asiki, S.F.M.).

Romuald P Boua (RP)

Institut de Recherche en Sciences de la Sante, Clinical Research Unit of Nanoro, Burkina Faso (R.P.B., H.S.).

F Xavier Gómez-Olivé (FX)

MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (F.X.G.-O., S.T.).

Felistas Mashinya (F)

Department of Pathology and Medical Science, School of Health Care Sciences, Faculty of Health Sciences, University of Limpopo, Polokwane, South Africa (M.A., F. Mashinya).

Lisa Micklesfield (L)

MRC/Wits Developmental Pathways for Health Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (L.M., S.A.N.).

Shukri F Mohamed (SF)

African Population and Health Research Center, Nairobi, Kenya (G. Asiki, S.F.M.).

Engelbert A Nonterah (EA)

Navrongo Health Research Centre, Ghana (G. Agongo, E.A.N.).

Shane A Norris (SA)

MRC/Wits Developmental Pathways for Health Research Unit, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (L.M., S.A.N.).

Hermann Sorgho (H)

Institut de Recherche en Sciences de la Sante, Clinical Research Unit of Nanoro, Burkina Faso (R.P.B., H.S.).

Stephen Tollman (S)

MRC/Wits Rural Public Health and Health Transitions Research Unit (Agincourt), School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (F.X.G.-O., S.T.).

Rulan S Parekh (RS)

Departments of Pediatrics, Medicine and Epidemiology, Hospital for Sick Children, University Health Network and University of Toronto, Canada (R.S.P.).

Chishala Chishala (C)

Division of Cardiology, Department of Medicine (M.E.E., C.C.), University of Cape Town, South Africa.

Kenneth Ekoru (K)

Center for Research on Genomics and Global Health, National Human Genome Research Institute, National Institutes of Health, Bethesda, MD (K.E.).

Salina P Waddy (SP)

Department of Neurology, Atlanta Veterans Affairs Medical Center, Decatur, GA (S.P.W.).

Emmanuel Peprah (E)

College of Global Public Health, New York University, New York, NY (E.P.).

George A Mensah (GA)

Center for Translation Research and Implementation Science, National Heart, Lung, and Blood Institute, NIH, Bethesda, MD (G.A.M.).

Ken Wiley (K)

Division of Genomic Medicine, National Human Genome Research Institute, Bethesda, MD (K. Wiley).

Jennifer Troyer (J)

Human Heredity and Health in Africa, Division of Genome Sciences (J.T.), National Institutes of Health, Bethesda, MD.

Michèle Ramsay (M)

Sydney Brenner Institute for Molecular Bioscience and Division of Human Genetics, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa (O.M.A., F. Made, S.A.A., M.R.).

Mayowa O Owolabi (MO)

From the Center for Genomic and Precision Medicine, College of Medicine, (O.M.A., B.S., R.A., M.O.O.), University of Ibadan, Ibadan, Nigeria.

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