Saraf-dependent activation of mTORC1 regulates cardiac growth.

Amino Acid Sequence Animals Animals, Newborn Base Sequence Calcium Signaling Calcium-Binding Proteins / chemistry Cell Proliferation Cell Size Electrocardiography Gene Knockdown Techniques Heart / growth & development Heart Function Tests Homeostasis Humans Mechanistic Target of Rapamycin Complex 1 / metabolism Membrane Proteins Mice, Inbred C57BL Mice, Knockout Myocytes, Cardiac / metabolism Rats
Calcium Hypertrophy Saraf mTORC1

Journal

Journal of molecular and cellular cardiology
ISSN: 1095-8584
Titre abrégé: J Mol Cell Cardiol
Pays: England
ID NLM: 0262322

Informations de publication

Date de publication:
04 2020
Historique:
received: 16 05 2019
revised: 03 03 2020
accepted: 09 03 2020
pubmed: 17 3 2020
medline: 29 5 2021
entrez: 17 3 2020
Statut: ppublish

Résumé

Pathological cardiac hypertrophy is an independent risk for heart failure (HF) and sudden death. Deciphering signaling pathways regulating intracellular Ca

Identifiants

DOI: 10.1016/j.yjmcc.2020.03.004 PMID: 32173353
pubmed: 32173353
pii: S0022-2828(20)30059-6
doi: 10.1016/j.yjmcc.2020.03.004
pii:
doi:

Substances chimiques

Calcium-Binding Proteins 0
Membrane Proteins 0
Saraf protein, mouse 0
Mechanistic Target of Rapamycin Complex 1 EC 2.7.11.1

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

30-42

Informations de copyright

Copyright © 2020 Elsevier Ltd. All rights reserved.

Déclaration de conflit d'intérêts

Declaration of Competing Interest None

Auteurs

Ayse Sanlialp (A)

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 669, 69120 Heidelberg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Dagmar Schumacher (D)

DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany; Institute of Pharmacology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany.

Leon Kiper (L)

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 669, 69120 Heidelberg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Eshita Varma (E)

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 669, 69120 Heidelberg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Eva Riechert (E)

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 669, 69120 Heidelberg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Thanh Cao Ho (TC)

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 669, 69120 Heidelberg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Christoph Hofmann (C)

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 669, 69120 Heidelberg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Vivien Kmietczyk (V)

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 669, 69120 Heidelberg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Frank Zimmermann (F)

Interfacultary Biomedical Faculty (IBF), University of Heidelberg, Im Neuenheimer Feld 347, 69120 Heidelberg, Germany.

Sascha Dlugosz (S)

Interfacultary Biomedical Faculty (IBF), University of Heidelberg, Im Neuenheimer Feld 347, 69120 Heidelberg, Germany.

Angela Wirth (A)

DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany; Institute of Pharmacology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany.

Agnieszka A Gorska (AA)

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 669, 69120 Heidelberg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Jana Burghaus (J)

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 669, 69120 Heidelberg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Juan E Camacho Londoño (JE)

DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany; Institute of Pharmacology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany.

Hugo A Katus (HA)

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 669, 69120 Heidelberg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Shirin Doroudgar (S)

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 669, 69120 Heidelberg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany.

Marc Freichel (M)

DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany; Institute of Pharmacology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 366, 69120 Heidelberg, Germany.

Mirko Völkers (M)

Department of Cardiology, Angiology, and Pneumology, University Hospital Heidelberg, University of Heidelberg, Im Neuenheimer Feld 669, 69120 Heidelberg, Germany; DZHK (German Center for Cardiovascular Research), Partner Site Heidelberg/Mannheim, 69120 Heidelberg, Germany. Electronic address: mirko.voelkers@med.uni-heidelberg.de.

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Classifications MeSH

questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Données de séquences moléculaires › Séquence d'acides aminés › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Eucaryotes › Animaux › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Eucaryotes › Animaux › Groupes animaux › Animaux nouveau-nés › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Sciences de l'information › Sources d'information › Services d'information › Documentation › Données de séquences moléculaires › Séquence nucléotidique › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Systèmes de seconds messagers › Signalisation calcique › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de transport › Protéines de liaison au calcium › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Phénomènes physiologiques › Croissance et développement › Croissance › Processus de croissance cellulaire › Prolifération cellulaire › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Taille de la cellule › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Électrodiagnostic › Électrocardiographie › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Techniques d'investigation › Techniques génétiques › Ciblage de gène › Techniques de knock-down de gènes › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Système cardiovasculaire › Coeur › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Diagnostic › Techniques et procédures diagnostiques › Techniques de diagnostic cardiovasculaire › Tests de la fonction cardiaque › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Phénomènes physiologiques › Homéostasie › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines et peptides de signalisation intracellulaire › Protein-Serine-Threonine Kinases › Sérine-thréonine kinases TOR › Complexe-1 cible mécanistique de la rapamycine › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines membranaires › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée C57BL › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Cellules › Cellules musculaires › Myocytes cardiaques › Saraf-dependent activation of mTORC1 regulates...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Rats › Saraf-dependent activation of mTORC1 regulates...