New Advances in Fabrication of Graphene Glyconanomaterials for Application in Therapy and Diagnosis.


Journal

ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658

Informations de publication

Date de publication:
10 Mar 2020
Historique:
received: 17 12 2019
accepted: 20 02 2020
entrez: 17 3 2020
pubmed: 17 3 2020
medline: 17 3 2020
Statut: epublish

Résumé

Glycoderivatives are an important class of molecules with enormous relevance in numerous biological phenomena; therefore, they have a key role in the learning, understanding, and assessment of different diseases. Nanotechnology, and in particular the design of new nanomaterials, is one of the areas of greatest interest today. In this case, graphene nanomaterials represent very interesting platforms for studying glycosystems, glyconanomaterials that combine the biomolecular recognition and the characteristics of nanoscale objects in the development of early diagnosis systems, and efficient specific therapeutic modalities. In this mini-review, we discuss some results recently described in the literature on the conjugation of graphene materials and carbohydrates through the selective interaction of glycoenzymes in graphene to create new materials with biosensing applications, the development and application of sugar-graphene composites, and finally biosystems combining the properties of graphene with metallic nanoparticles and sugars for the creation of excellent glyconanomaterials as novel systems for the therapy or diagnosis of important diseases such as cancer or diabetes.

Identifiants

pubmed: 32175483
doi: 10.1021/acsomega.9b04332
pmc: PMC7066556
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

4362-4369

Informations de copyright

Copyright © 2020 American Chemical Society.

Déclaration de conflit d'intérêts

The authors declare no competing financial interest.

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Auteurs

Noelia Losada-Garcia (N)

Department of Biocatalysis, Institute of Catalysis (CSIC), Marie Curie 2, Cantoblanco Campus UAM, Madrid 28049, Spain.

Ivan Rodriguez-Oliva (I)

Department of Biocatalysis, Institute of Catalysis (CSIC), Marie Curie 2, Cantoblanco Campus UAM, Madrid 28049, Spain.

Milica Simovic (M)

Department of Biochemical Engineering and Biotechnology, Faculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, Belgrade 11000, Serbia.

Dejan I Bezbradica (DI)

Department of Biochemical Engineering and Biotechnology, Faculty of Technology and Metallurgy, University of Belgrade, Karnegijeva 4, Belgrade 11000, Serbia.

Jose M Palomo (JM)

Department of Biocatalysis, Institute of Catalysis (CSIC), Marie Curie 2, Cantoblanco Campus UAM, Madrid 28049, Spain.

Classifications MeSH