Protease-Catalyzed l-Aspartate Oligomerization: Substrate Selectivity and Computational Modeling.
Journal
ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658
Informations de publication
Date de publication:
10 Mar 2020
10 Mar 2020
Historique:
received:
04
10
2019
accepted:
11
12
2019
entrez:
17
3
2020
pubmed:
17
3
2020
medline:
17
3
2020
Statut:
epublish
Résumé
Poly(aspartic acid) (PAA) is a biodegradable water-soluble anionic polymer that can potentially replace poly(acrylic acid) for industrial applications and has shown promise for regenerative medicine and drug delivery. This paper describes an efficient and sustainable route that uses protease catalysis to convert l-aspartate diethyl ester (Et
Identifiants
pubmed: 32175488
doi: 10.1021/acsomega.9b03290
pmc: PMC7066554
doi:
Types de publication
Journal Article
Langues
eng
Pagination
4403-4414Subventions
Organisme : NIGMS NIH HHS
ID : R01 GM132565
Pays : United States
Informations de copyright
Copyright © 2020 American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare no competing financial interest.
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