Quinolinecarboxamides Inhibit the Replication of the Bovine Viral Diarrhea Virus by Targeting a Hot Spot for the Inhibition of Pestivirus Replication in the RNA-Dependent RNA Polymerase.


Journal

Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009

Informations de publication

Date de publication:
12 Mar 2020
Historique:
received: 31 01 2020
revised: 06 03 2020
accepted: 10 03 2020
entrez: 18 3 2020
pubmed: 18 3 2020
medline: 18 12 2020
Statut: epublish

Résumé

The bovine viral diarrhea virus (BVDV), a pestivirus from the family of

Identifiants

pubmed: 32178258
pii: molecules25061283
doi: 10.3390/molecules25061283
pmc: PMC7144022
pii:
doi:

Substances chimiques

Quinolines 0
quinoline-4-carboxamide 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : Belgian Federal Science Policy Office
ID : BELVIR
Organisme : KU Leuven
ID : GOA 10/14

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Auteurs

Simone Musiu (S)

KU Leuven University, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, Leuven, Herestraat 49, B-3000 Leuven, Belgium.

Yunierkis Perez Castillo (YP)

Bio-Cheminformatics Research Group and Escuela de Ciencias Físicas y Matemáticas, Universidad de Las Americas, 170150 Quito, Ecuador.

Alexandra Muigg (A)

Institut für Pharmazie, Abteilung Pharmazeutische Chemie, Universität Innsbruck, Innrain 80/82, A-6020 Innsbruck, Austria.

Gerhard Pürstinger (G)

Institut für Pharmazie, Abteilung Pharmazeutische Chemie, Universität Innsbruck, Innrain 80/82, A-6020 Innsbruck, Austria.

Pieter Leyssen (P)

KU Leuven University, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, Leuven, Herestraat 49, B-3000 Leuven, Belgium.

Mathy Froeyen (M)

KU Leuven University, Department of Pharmaceutical and Pharmacological Sciences, Laboratory of Medicinal Chemistry, Rega Institute for Medical Research, Leuven, Herestraat 49, B-3000 Leuven, Belgium mathy.froeyen@kuleuven.be.

Johan Neyts (J)

KU Leuven University, Department of Microbiology and Immunology, Laboratory of Virology and Chemotherapy, Rega Institute for Medical Research, Leuven, Herestraat 49, B-3000 Leuven, Belgium.

Jan Paeshuyse (J)

KU Leuven, Division Animal and Human Health Engineering, Laboratory for host pathogen interactions, Kasteelpark Arenberg 30, 3001 Leuven, Belgium.

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Classifications MeSH