Allogeneic Hematopoietic Stem Cell Transplantation in a Rare Case of Tonsillar Mast Cell Sarcoma.
allogeneic stem cell transplantation
mast cell neoplasm
mast cell sarcoma
poor prognosis
rare disease (RD)
Journal
Frontiers in oncology
ISSN: 2234-943X
Titre abrégé: Front Oncol
Pays: Switzerland
ID NLM: 101568867
Informations de publication
Date de publication:
2020
2020
Historique:
received:
17
12
2019
accepted:
07
02
2020
entrez:
18
3
2020
pubmed:
18
3
2020
medline:
18
3
2020
Statut:
epublish
Résumé
Mast cell sarcoma comprises a rare aggressive mast cell neoplasia with histological, clinical, and genetic features distinct from other mast cell neoplasm. Until now, prognosis is still poor due to high rates of progression to mast cell leukemia and failure of conventional chemotherapies. Our here presented first report about successful allogeneic hematopoietic stem cell transplantation leading to remission in a case of tonsillar MCS represents a promising potential curative treatment option for this rare and often fatal disease.
Identifiants
pubmed: 32181155
doi: 10.3389/fonc.2020.00219
pmc: PMC7059127
doi:
Types de publication
Case Reports
Langues
eng
Pagination
219Informations de copyright
Copyright © 2020 Kubasch, Franke, Aldaoud, Weibl, Jentzsch, Sabri, Horny, Fend, Behre, Platzbecker and Vucinic.
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