Age-dependent increase in Thy-1 protein in the rat supraoptic nucleus.
Cell biology
Cell death
Dual-label fluorescence
Magnocellular neurosecretory system
Membrane
Nervous system
Neural lobe
Neuronal death
Neuroscience
Western blot
ß3 integrin
ß5 integrin
αv integrin
Journal
Heliyon
ISSN: 2405-8440
Titre abrégé: Heliyon
Pays: England
ID NLM: 101672560
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
received:
12
08
2019
revised:
15
10
2019
accepted:
24
02
2020
entrez:
18
3
2020
pubmed:
18
3
2020
medline:
18
3
2020
Statut:
epublish
Résumé
Mature mammalian CNS neurons often do not recover successfully following injury. To this point, unilateral lesion of the hypothalamo-neurohypophysial tract results in collateral sprouting from uninjured axons of the supraoptic nucleus (SON) in 35-day-old but not in 125-day-old rats. Thus, it appears that there are age-related changes within the SON that preclude the older rat from recovering following axotomy. We hypothesize that the intrinsic capacity for axon reorganization may depend, in part, on age-related alterations in cell adhesion molecules that allow normal astrocyte-neuron interactions in the SON. In support of our hypothesis, numerous reports have shown that Thy-1 is increased in neurons at the cessation of axon outgrowth. Therefore, we compared protein levels of Thy-1 and the Thy-1 interacting integrin subunits, alpha-v (α
Identifiants
pubmed: 32181386
doi: 10.1016/j.heliyon.2020.e03501
pii: S2405-8440(20)30346-7
pii: e03501
pmc: PMC7066247
doi:
Types de publication
Journal Article
Langues
eng
Pagination
e03501Informations de copyright
© 2020 The Authors.
Références
Curr Biol. 2001 Jul 10;11(13):1028-38
pubmed: 11470407
J Neurosci. 2012 Jul 4;32(27):9277-87
pubmed: 22764235
Proc Natl Acad Sci U S A. 1995 Nov 21;92(24):11195-9
pubmed: 7479964
Mol Cell Neurosci. 2005 Feb;28(2):229-40
pubmed: 15691705
Exp Neurol. 2013 Feb;240:75-87
pubmed: 23123407
J Anat. 1970 Jul;107(Pt 1):187
pubmed: 5473280
Biochim Biophys Acta. 2008 Jun;1783(6):1111-20
pubmed: 18346467
Neuroscience. 1998 Dec;87(3):571-82
pubmed: 9758224
J Mol Neurosci. 2010 Mar;40(3):269-83
pubmed: 19499350
Development. 1990 Aug;109(4):851-64
pubmed: 1977576
J Comp Neurol. 2000 May 29;421(2):215-33
pubmed: 10813783
J Neuroimmunol. 1982 Jun;2(3-4):191-200
pubmed: 7085861
Br Med J. 1964 Dec 26;2(5425):1619-25
pubmed: 14213072
Rom J Morphol Embryol. 2008;49(3):279-302
pubmed: 18758632
Biol Res. 2002;35(2):231-8
pubmed: 12415741
J Comp Neurol. 2019 Oct 1;527(14):2291-2301
pubmed: 30861131
J Anat. 1971 May;109(Pt 1):97-114
pubmed: 4104151
J Histochem Cytochem. 1974 Dec;22(12):1077-83
pubmed: 4374474
Nature. 1979 Aug 23;280(5724):688-90
pubmed: 471047
J Comp Neurol. 2001 Jun 11;434(4):413-27
pubmed: 11343290
J Neurosci. 1982 Jun;2(6):663-73
pubmed: 7045293
Cell Tissue Res. 1985;242(1):9-15
pubmed: 2412700
Neurobiol Aging. 2010 Jun;31(6):1003-9
pubmed: 18755527
Nature. 1992 Feb 20;355(6362):745-8
pubmed: 1346926
J Cell Commun Signal. 2015 Sep;9(3):217-31
pubmed: 25698661
J Cell Mol Med. 2008 Dec;12(6B):2731-53
pubmed: 18266980
Annu Rev Neurosci. 2007;30:451-74
pubmed: 17600523
Psychopharmacology (Berl). 1996 Apr;124(3):288-90
pubmed: 8740054
Mol Cell Neurosci. 2007 Jun;35(2):249-60
pubmed: 17433878
Exp Neurol. 1991 Jan;111(1):9-24
pubmed: 1984437
Curr Biol. 1998 Aug 27;8(17):983-6
pubmed: 9742403
Gen Comp Endocrinol. 1962 Apr;2:215-28
pubmed: 14475196
J Biol Chem. 2004 Sep 10;279(37):39139-45
pubmed: 15220352
Brain Res. 1985 Mar 18;330(1):189-93
pubmed: 3886075
Exp Neurol. 2006 Jan;197(1):206-14
pubmed: 16226750
Cell Tissue Res. 1974;155(4):541-54
pubmed: 4375008
Int Rev Cell Mol Biol. 2013;305:163-216
pubmed: 23890382
BMC Neurosci. 2007 Jun 29;8:44
pubmed: 17603879
Dev Cell. 2010 May 18;18(5):725-36
pubmed: 20493807
J Cell Sci. 2009 Oct 1;122(Pt 19):3462-71
pubmed: 19723805
Exp Neurol. 2009 Jan;215(1):135-41
pubmed: 18973757
J Biol Chem. 2010 Jul 16;285(29):22382-93
pubmed: 20463011
Microsc Res Tech. 2002 Jan 15;56(2):101-12
pubmed: 11810713
PLoS One. 2012;7(3):e34295
pubmed: 22479590
J Cell Biol. 1993 Jul;122(1):181-9
pubmed: 8100230
Exp Neurol. 2011 Oct;231(2):284-94
pubmed: 21806987
Development. 1991 May;112(1):161-76
pubmed: 1685113
J Neurosci Methods. 2005 Jul 15;146(1):42-9
pubmed: 15935219
Immunol Ser. 1989;45:121-48
pubmed: 2577315
J Neuroendocrinol. 2003 Oct;15(10):933-9
pubmed: 12969237
Exp Neurol. 2012 Jan;233(1):243-52
pubmed: 22037350
Cell Commun Signal. 2013 May 21;11:35
pubmed: 23693126
J Neurosci. 1999 Mar 1;19(5):1586-98
pubmed: 10024346
Brain Res. 1984 Mar 26;296(1):87-91
pubmed: 6143594
Brain Res. 1973 Jun 15;55(2):245-61
pubmed: 4714005
J Comp Neurol. 1998 May 4;394(2):252-69
pubmed: 9552130
Z Zellforsch Mikrosk Anat. 1957;46(6):686-709
pubmed: 13531620
Lab Invest. 1980 Oct;43(4):342-51
pubmed: 6160316