Light and electron microscopic studies on the pecten oculi showing blood-retina barrier properties in Turkey's native Gerze chicken.
Cadherin
Gerze chicken
immunohistochemistry
pecten oculi
scanning electron microscopy
Journal
Anatomia, histologia, embryologia
ISSN: 1439-0264
Titre abrégé: Anat Histol Embryol
Pays: Germany
ID NLM: 7704218
Informations de publication
Date de publication:
Jul 2020
Jul 2020
Historique:
received:
16
07
2019
accepted:
28
02
2020
pubmed:
18
3
2020
medline:
17
3
2021
entrez:
18
3
2020
Statut:
ppublish
Résumé
The pecten oculi is a highly vascularized and pigmented organ that projects from the optic disc into the vitreous body in the avian eye. In this study, the pecten oculi of Turkey's native Gerze chicken was examined by light and scanning electron microscopy. Furthermore, the localization of some adherens junction components (E-cadherin and pan-cadherin) in intact vessels of the blood-retina barrier was investigated by immunohistochemistry. In the Gerze chicken, the pecten oculi was a thin structure, which was located over the head of the discus nervi optici and projected from the retina into the corpus vitreum. The pecten oculi consisted of 18-21 highly vascularized pleats, joined apically by a bridge and resembled an accordion in appearance. Hyalocytes and melanocytes were observed around the small and large vessels. The morphometric data of the pecten oculi showed that there were no statistical differences in terms of sex. The immunohistochemical analysis of the pecten oculi, which is used as a model for the investigation of the formation and maturation of the barrier properties in the central nervous system, revealed cytoplasmic E-cadherin and pan-cadherin immunoreactivity in the endothelial cells of the small, large and capillary vessels. These observations suggest that while the morphological and histological structure of the Gerze chicken's pecten oculi was generally similar to that of other diurnal domestic birds, the pecten oculi, a model system for vascular differentiation and the blood-retina barrier, expressed different cadherins.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
478-485Informations de copyright
© 2020 Blackwell Verlag GmbH.
Références
Bachsich, P., & Gellert, A. (1935). Beiträge zur kenntnis der struktur und funktion des pectens im vogelauge. Graefes Archive for Clinical and Experimental Ophthalmology, 133(3), 448-460.
Baumel, J. J., King, A. S., Breazile, J. E., Evans, H. E., & Vanden Berge, J. C. (1993). Handbook of avian anatomy: Nomina Anatomica avium, 2nd ed. Massachusetts, MA: Cambridge.
Bawa, S. R., & Yashroy, R. C. (1972). Effect of dark and light adaptation on the retina and pecten of chicken. Experimental Eye Research, 13(1), 92-97.
Bazzoni, G., & Dejana, E. (2004). Endothelial cell-to-cell junctions: Molecular organization and role in vascular homeostasis. Physiological Reviews, 84, 869-901.
Brach, V. (1977). The functional significance of the avian pecten, a review. Condor, 79(3), 321-327.
Braekevelt, C. R. (1990). Fine structure of the pecten oculi of the mallard (Anas platyrhynchos). Canadian Journal of Zoology, 68, 427-432.
Braekevelt, C. R. (1991). Fine structure of the pecten oculi of the red-tailed hawk (Buteo jamaicensis). Anatomia, Histologia, Embryologia, 20, 354-362.
Braekevelt, C. R. (1993). Fine structure of the pecten oculi in the great horned owl (Bubo virginianus). Histology and Histopathology, 8, 9-15.
Braekevelt, C. R. (1994). Fine structure of the pecten oculi in the American crow (Corvus brachyrhynchos). Anatomia, Histologia, Embryologia, 23, 357-366.
Braekevelt, C. R. (1998). Fine structure of the pecten oculi of the emu (Dromaius novaehollandiae). Tissue and Cell, 30, 157-165.
Braekevelt, C. R., & Richardson, K. C. (1996). Fine structure of the pecten oculi in the Australian galah (Eolophus roseicapillus) (Aves). Histology and Histopathology, 11, 565-571.
Brown, R. C., & Davis, T. P. (2002). Calcium modulation of adherens and tight junction function: A potential mechanism for blood brain barrier disruption after stroke. Stroke, 33, 1706-1711.
Corona, M., Scala, G., & Perrella, A. (2004). Angioarchitecture of the duck pecten. Biomed Research International, 15, 19-25.
Crossman, G. A. (1937). Modification of Mallory’s connective tissue stain with a discussion of the principles involved. Anatomical Record, 69, 33-34.
Crozier, W. J., & Wolf, E. (1944). Flicker response contours for the sparrow and the theory of the avian pecten. Journal of General Psychology, 27, 315-324.
Dayan, M. O., & Ozaydin, T. A. (2013). Comparative morphometrical study of the pecten oculi in different avian species. The Scientific World Journal. Article ID, 968652, 5 pp.
Duke-Elder, S. (1958). System of ophthalmology, 2nd ed. London, UK: Henry Kimpton Publishers.
Frost, J. B., & Mouristen, H. (2006). The neural mechanisms of long distance animal navigation. Current Opinion in Neurobiology, 16(4), 481-488.
Geiger, B., Volberg, T., Ginsberg, D., Bitzur, S., Sabanay, I., & Hynes, R. O. (1990). Broad spectrum pan-cadherin antibodies, reactive with the C-terminal 24 amino acid residues of N-cadherin. Journal of Cell Science, 97, 607-614.
Gerhardt, H., Liebner, S., & Wolburg, H. (1996a). The pecten oculi of the chicken as a new in vivo model of the blood-brain barrier. Cell Tissue Research, 285, 91-100.
Gerhardt, H., Liebner, S., & Wolburg, H. (1996b). Blood-retina barrier properties of the pecten oculi of the chicken. In P.-O. Couraud, & D. Scherman (Eds.), Biology and physiology of the blood-brain barrier (pp. 79-80). New York, NY: Plenum Press.
Gezer Ince, N., Onuk, B., Kabak, Y. B., Alan, A., & Kabak, M. (2017). Macroanatomic, light, and electron microscopic examination of pecten oculi in the seagull (Larus canus). Microscopy Research and Technique, 80(7), 787-792.
Henis, M. E. G., Ahmed, K. A., Ibrahim, I. A., & Saleh, A. M. (2014). Light and electron microscopical studies on the hyalocytes of turkey (Meleagris Gallopavo). Journal of Advanced Veterinary Research, 5, 8-13.
Hirase, T., Staddon, J. M., Saitou, M., Ando-Akatsuka, Y., Itoh, M., Furuse, M., … Rubin, L. L. (1997). Occludin as a possible determinant of tight junction permeability in endothelial cells. Journal of Cell Science, 110, 1603-1613.
Hodges, R. (1974). The histology of the fowl, 1st ed. London, UK: Academic Press.
Itoh, M., Nagafuchi, A., Moroi, S., & Tsukita, S. (1997). Involvement of ZO1 in cadherin-based cell adhesion through its direct binding to α catenin and actin filaments. Journal of Cell Biology, 138, 181-192.
Kiama, S. G., Bhattacharjee, J., Maina, J. N., & Weyrauch, K. D. (1994). A scanning electron microscope study of the pecten oculi of the black kite (Milvus migrans): Possible involvement of melanosomes in protecting the pecten against damage by ultraviolet light. Journal of Anatomy, 185, 637-642.
Kiama, S. G., Maina, J. N., Bhattacharjee, J., Mwangi, D. K., Macharia, R. G., & Weyrauch, K. D. (2006). The morphology of the pecten oculi of the ostrich, Struthio camelus. Annals of Anatomy- Anatomischer Anzeiger, 188, 519-528.
Kiama, S. G., Maina, J. N., Bhattacharjee, J., & Weyrauch, K. D. (2001). Functional morphology of the pecten oculi in the nocturnal spotted eagle owl (Bubo bubo africanus), and the diurnal black kite (Milvus migrans) and domestic fowl (Gallus gallus var. domesticus): A comparative study. Journal of Zoology, 254(4), 521-528.
Kiama, S. G., Maina, J. N., Bhattacharjee, J., Weyrauch, K. D., & Gehr, P. (1998). A scanning electron microscope study of the luminal surface specializations in the blood vessels of the pecten oculi in a diurnal bird, the black kite (Milvus migrans). Annals of Anatomy- Anatomischer Anzeiger, 180, 455-460.
King, A. S., & Mclelland, J. (1984). Birds, special sense organs, 2nd ed. London, UK: Bailliere Tindall Publishers.
Liebner, S., Gerhardt, H., & Wolburg, H. (1997). Maturation of the blood-retina barrier in the pecten oculi of the developing chicken. Developmental Brain Research, 100, 205-219.
Liombart, C., Nacher, V., Ramos, D., Luppo, M., Carretero, A., Navarro, M., … Ruberte, J. (2009). Morphological characterization of pecteneal hyalocytes in the developing quail retina. Journal of Anatomy, 215, 280-291.
Lum, H., & Malik, A. B. (1994). Regulation of vascular endothelial barrier function. American Journal of Physiology, 267, L223-L241.
Micali, A., Pisani, A., Ventrici, C., Puzzolo, D., Roszkowska, A. M., Spinella, R., & Aragona, P. (2012). Morphological and morphometric study of the pecten oculi in the budgerigar (Melopsittacus undulatus). Anatomical Record, 295, 540-550.
Onuk, B., Tutuncu, S., Alan, A., Kabak, M., & Gezer Ince, N. (2013). Macroanatomic, light and scanning electron microscopic studies of the pecten oculi in the stork (Ciconia ciconia). Microscopy Research Technique, 76, 963-967.
Orhan, I. O., Ekim, O., & Bayraktaroğlu, A. G. (2011). Morphological investigation of the pecten oculi in quail (Coturnix coturnix japonica). Ankara Universitesi Veteriner Fakultesi Dergisi, 58, 5-10.
Pourlis, A. F. (2013). Scanning electron microscopic studies of the pecten oculi in the quail (Coturnix coturnix japonica). Anatomy Research International. Article ID: 650601, 6 pages.
Rahman, M. L., Lee, E., Aoyama, M., & Sugita, S. (2010). Light and electron microscopy study of the pecten oculi of the jungle crow (Corvus macrorhynchos). Okajimas Folia Anatomica Japonica., 87, 75-83.
Rubinek, T., Yu, R., Hadaii, M., Barkai, G., Nass, D., Melmed, S., & Shimon, I. (2003). The cell adhesion molecules N-cadherin and neural cell adhesion molecule regulate human growth hormone: A novel mechanism for regulating pituitary hormone secretion. Journal of Clinical Endocrinology and Metabolism, 88, 3724-3730.
Staddon, J. M., & Rubin, L. L. (1996). Cell adhesion, cell junctions and the blood-brain barrier. Current Opinion in Neurobiology, 6, 622-627.
Takeichi, M. (1990). Cadherins: A molecular family important in selective cell-cell adhesion. Annual Review of Biochemistry, 59, 237-252.
Uehara, M., Imagawa, T., & Kitagawa, H. (1996). Morphological studies of the hyalocytes in the chicken eye: Scanning electron microscopy and inflammatory response after the intravitreous injection of carbon particles. Journal of Anatomy, 188, 661-669.
Vincent, P. A., Xiao, K., Buckley, K. M., & Kowalczyk, A. P. (2004). VE-cadherin: Adhesion at arm’s length. The American Journal of Physiology-Cell Physiology, 286, C987-997.
Walls, G. L. (1942). The vertebrate eye and its adaptive radiation, 1st ed. Michigan, MI: Cranbrook Institute of Science.
Wheelock, M. J., & Johnson, K. R. (2003). Cadherins as modulators of cellular phenotype. Annual Review of Cell and Developmental Biology, 19, 207-235.
Wilcox, R. R. (2010). Fundamentals of modern statistical methods, 2nd ed. New York, NY: Springer.
Wolburg, H., Liebner, S., Reichenbach, A., & Gerhardt, H. (1999). The pecten oculi of the chicken: A model system for vascular differentiation and barrier maturation. International Review of Cytology, 187, 111-159.
Wu, P., Gong, H., Richman, R., & Freddo, T. F. (2000). Localization of occludin, ZO-1, and pan-cadherin in rabbit ciliary epithelium and iris vascular endothelium. Histochemistry and Cell Biology, 114, 303-310.