Disorders of Puberty: Endocrinology of the Pre-Pubertal Testis.
AMH
IGF1
Sertoli cell dysfunction
Sertoli cells
inhibin B
insulin
male infertility
Journal
Journal of clinical medicine
ISSN: 2077-0383
Titre abrégé: J Clin Med
Pays: Switzerland
ID NLM: 101606588
Informations de publication
Date de publication:
13 Mar 2020
13 Mar 2020
Historique:
received:
11
03
2020
accepted:
11
03
2020
entrez:
19
3
2020
pubmed:
19
3
2020
medline:
19
3
2020
Statut:
epublish
Résumé
Male infertility is a widespread condition among western countries. Meta-regression data show that sperm concentration and total sperm count have halved in the last decades. The reasons of this decline are still unclear. The evaluation of testicular function in pre-pubertal children may be effective in the timely detection of Sertoli cell (SC) disfunction, which anticipates the diagnosis of male infertility. The aim of this Special Issue is to gather together in vitro evidence on SC physiology, causes of SC dysfunction, and to suggest a practical approach to be adopted in children.
Identifiants
pubmed: 32182985
pii: jcm9030780
doi: 10.3390/jcm9030780
pmc: PMC7141315
pii:
doi:
Types de publication
Editorial
Langues
eng
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