Effect of Gellan Gum/Tuna Skin Film in Guided Bone Regeneration in Artificial Bone Defect in Rabbit Calvaria.
gellan gum
guided bone regeneration
membrane
tuna skin gelatin
Journal
Materials (Basel, Switzerland)
ISSN: 1996-1944
Titre abrégé: Materials (Basel)
Pays: Switzerland
ID NLM: 101555929
Informations de publication
Date de publication:
14 Mar 2020
14 Mar 2020
Historique:
received:
28
01
2020
revised:
05
03
2020
accepted:
10
03
2020
entrez:
19
3
2020
pubmed:
19
3
2020
medline:
19
3
2020
Statut:
epublish
Résumé
It is necessary to prevent the invasion of soft tissue into bone defects for successful outcomes in guided bone regeneration (GBR). For this reason, many materials are used as protective barriers to bone defects. In this study, a gellan gum/tuna skin gelatin (GEL/TSG) film was prepared, and its effectiveness in bone regeneration was evaluated. The film exhibited average cell viability in vitro. Experimental bone defects were prepared in rabbit calvaria, and a bone graft procedure with beta-tricalcium phosphate was done. The film was used as a membrane of GBR and compared with results using a commercial collagen membrane. Grafted material did not show dispersion outside of bone defects and the film did not collapse into the bone defect. New bone formation was comparable to that using the collagen membrane. These results suggest that the GEL/TSG film could be used as a membrane for GBR.
Identifiants
pubmed: 32183273
pii: ma13061318
doi: 10.3390/ma13061318
pmc: PMC7142440
pii:
doi:
Types de publication
Journal Article
Langues
eng
Subventions
Organisme : National Research Foundation of Korea
ID : NRF-2017R1D1A1A02017564
Organisme : Chonnam National University Hospital Biomedical Research Institute
ID : CRU17035-22
Références
J Periodontal Implant Sci. 2015 Dec;45(6):229-37
pubmed: 26732806
J Dent Res. 2014 Dec;93(12):1187-95
pubmed: 25139365
ACS Appl Mater Interfaces. 2019 Jun 12;11(23):20589-20602
pubmed: 31120238
Biomaterials. 2005 Jun;26(18):3793-9
pubmed: 15626427
Biofabrication. 2017 Aug 21;9(4):044101
pubmed: 28770808
Clin Oral Implants Res. 1994 Jun;5(2):66-74
pubmed: 7918911
Mater Sci Eng C Mater Biol Appl. 2017 Sep 1;78:1246-1262
pubmed: 28575964
J Mater Sci Mater Med. 2012 Jan;23(1):51-61
pubmed: 22116662
Materials (Basel). 2019 Jun 27;12(13):
pubmed: 31252675
Soft Matter. 2014 Feb 7;10(5):672-87
pubmed: 24834901
Clin Oral Implants Res. 2004 Feb;15(1):101-11
pubmed: 14731183
J Periodontol. 2008 May;79(5):905-11
pubmed: 18454670
Int J Pharm. 2014 May 15;466(1-2):328-40
pubmed: 24657577
Acta Biomater. 2008 Sep;4(5):1226-34
pubmed: 18434266
ACS Appl Mater Interfaces. 2014 Nov 26;6(22):19668-79
pubmed: 25361388
Periodontol 2000. 2015 Jun;68(1):99-121
pubmed: 25867982
Eur J Oral Sci. 2017 Oct;125(5):315-337
pubmed: 28833567
Carbohydr Polym. 2012 Oct 15;90(3):1362-70
pubmed: 22939352
J Mater Sci Mater Med. 2011 Feb;22(2):263-71
pubmed: 21221734
J Dent Res. 2006 Nov;85(11):966-79
pubmed: 17062735
Appl Environ Microbiol. 1982 May;43(5):1086-91
pubmed: 16346007
J Prosthodont Res. 2013 Jan;57(1):3-14
pubmed: 23347794
Acta Biomater. 2016 Sep 1;41:119-32
pubmed: 27233132
J Can Dent Assoc. 2013;79:d1
pubmed: 23522126