Feedback Control of a Two-Component Signaling System by an Fe-S-Binding Receiver Domain.


Journal

mBio
ISSN: 2150-7511
Titre abrégé: mBio
Pays: United States
ID NLM: 101519231

Informations de publication

Date de publication:
17 03 2020
Historique:
entrez: 19 3 2020
pubmed: 19 3 2020
medline: 12 3 2021
Statut: epublish

Résumé

Two-component signaling systems (TCSs) function to detect environmental cues and transduce this information into a change in transcription. In its simplest form, TCS-dependent regulation of transcription entails phosphoryl-transfer from a sensory histidine kinase to its cognate DNA-binding receiver protein. However, in certain cases, auxiliary proteins may modulate TCSs in response to secondary environmental cues.

Identifiants

pubmed: 32184258
pii: mBio.03383-19
doi: 10.1128/mBio.03383-19
pmc: PMC7078487
pii:
doi:

Substances chimiques

Bacterial Proteins 0
Heme 42VZT0U6YR
Sulfur 70FD1KFU70
Iron E1UOL152H7
Histidine Kinase EC 2.7.13.1

Types de publication

Journal Article Research Support, N.I.H., Extramural

Langues

eng

Sous-ensembles de citation

IM

Subventions

Organisme : NIGMS NIH HHS
ID : R35 GM131762
Pays : United States
Organisme : NIGMS NIH HHS
ID : F32 GM128283
Pays : United States
Organisme : NIGMS NIH HHS
ID : R01 GM087353
Pays : United States

Informations de copyright

Copyright © 2020 Stein et al.

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Auteurs

Benjamin J Stein (BJ)

Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA.

Aretha Fiebig (A)

Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA.

Sean Crosson (S)

Department of Microbiology and Molecular Genetics, Michigan State University, East Lansing, Michigan, USA crosson4@msu.edu.

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