Inactivation of Non-Enveloped Viruses and Bacteria by an Electrically Charged Disinfectant Containing Meso-Structure Nanoparticles via Modification of the Genome.
E. coli
Salmonella
class I disinfectant
feline calicivirus
food safety
meso-structure
Journal
International journal of nanomedicine
ISSN: 1178-2013
Titre abrégé: Int J Nanomedicine
Pays: New Zealand
ID NLM: 101263847
Informations de publication
Date de publication:
2020
2020
Historique:
received:
04
09
2019
accepted:
24
12
2019
entrez:
19
3
2020
pubmed:
19
3
2020
medline:
22
5
2020
Statut:
epublish
Résumé
A previous study demonstrated the virucidal effect of an electrically charged disinfectant (CAC-717), which contains meso-structure nanoparticles, on enveloped viruses (influenza viruses). However, the effect of CAC-717 on other microorganisms and the mechanisms by which CAC-717 inactivates the microorganisms remain unclear. In this study, CAC-717 was further evaluated in terms of its biocidal and virucidal activity as well as its effect on bacterial and viral nucleic acids. The inactivation effects of CAC-717 against various microorganisms [non-enveloped virus, feline calicivirus (FCV); bacteria, Treatment of an equal volume of CAC-717 with cell lysate infected with a non-enveloped virus, feline calicivirus (FCV), reduced the TCID Our findings suggest that CAC-717 inactivates viruses and bacteria by modifying the viral and bacterial nucleic acids.
Identifiants
pubmed: 32184593
doi: 10.2147/IJN.S229880
pii: 229880
pmc: PMC7055524
doi:
Substances chimiques
Disinfectants
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
1387-1395Informations de copyright
© 2020 Sakudo et al.
Déclaration de conflit d'intérêts
K.F. and R.O. are employed by the Mineral Activation Technical Research Center and Santa Mineral Co., Ltd., respectively. The authors declare that they have no other conflicts of interest with the content of this article.
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