The Relationship Between the Striatal Dopaminergic Neuronal and Cognitive Function With Aging.
SPECT
Wechsler Adult Intelligence Scale
aging
cognitive function
dopamine transporter
verbal function
Journal
Frontiers in aging neuroscience
ISSN: 1663-4365
Titre abrégé: Front Aging Neurosci
Pays: Switzerland
ID NLM: 101525824
Informations de publication
Date de publication:
2020
2020
Historique:
received:
12
11
2019
accepted:
06
02
2020
entrez:
19
3
2020
pubmed:
19
3
2020
medline:
19
3
2020
Statut:
epublish
Résumé
Both cognitive function and striatal dopamine function decline by normal aging. However, the relationship among these three factors remains unclear. The aim of this study was to elucidate the association among age-related changes in the striatal dopamine transporter (DAT) and cognitive function in healthy subjects. The 30 healthy volunteers were enrolled in this research, the age ranged from 41 to 82 (64.5 ± 11.5, mean ± SD). All subjects were scanned with both T1-weighted magnetic resonance imaging (MRI) and
Identifiants
pubmed: 32184717
doi: 10.3389/fnagi.2020.00041
pmc: PMC7058549
doi:
Types de publication
Journal Article
Langues
eng
Pagination
41Informations de copyright
Copyright © 2020 Li, Hirano, Furukawa, Nakano, Kojima, Ishikawa, Tai, Horikoshi, Iimori, Uno, Matsuda and Kuwabara.
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