Histopathologic changes associated with Meibomian Gland dropout in a dog.


Journal

Veterinary ophthalmology
ISSN: 1463-5224
Titre abrégé: Vet Ophthalmol
Pays: England
ID NLM: 100887377

Informations de publication

Date de publication:
May 2020
Historique:
received: 17 07 2019
revised: 17 01 2020
accepted: 05 02 2020
pubmed: 19 3 2020
medline: 11 2 2021
entrez: 19 3 2020
Statut: ppublish

Résumé

To perform histopathologic analysis of tissue manifesting meibomian gland dropout on noncontact infrared meibography in a dog. A 14-year-old intact male Cairn terrier was evaluated at Triangle Animal Eye Clinic for dense corneal opacity of the right eye. A complete ocular examination was performed, including slit-lamp biomicroscopy, tonometry, and noncontact meibography. Pigmentary glaucoma with elevation of intraocular pressure was diagnosed, and meibography revealed morphological changes suggestive of gland dropout in the middle of the upper right eyelid. The globe was enucleated by the transpalpebral method, and palpebral tissue was subjected to histopathologic analysis. The analysis revealed an almost complete loss of meibomian gland structure accompanied by slight enlargement and proliferation of fibroblasts as well as by infiltration of plasma cells and lymphocytes. Meibomian gland dropout as detected by meibography can be associated with chronic inflammation.

Identifiants

pubmed: 32187833
doi: 10.1111/vop.12754
pmc: PMC7317917
doi:

Types de publication

Case Reports

Langues

eng

Sous-ensembles de citation

IM

Pagination

575-578

Informations de copyright

© 2020 The Authors. Veterinary Ophthalmology published by Wiley Periodicals, Inc. on behalf of American College of Veterinary Ophthalmologists.

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Auteurs

Yasunari Kitamura (Y)

Yakumo Animal Hospital, Hokkaido, Japan.

Reiko Arita (R)

Itoh Clinic, Saitama, Japan.

Yukihiro Miwa (Y)

Department of Ophthalmology, Keio University, Tokyo, Japan.

Hiroko Iwashita (H)

Triangle Animal Eye Clinic, Tokyo, Japan.

Akihiko Saito (A)

Triangle Animal Eye Clinic, Tokyo, Japan.

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Classifications MeSH