Great green tea ingredient? A narrative literature review on epigallocatechin gallate and its biophysical properties for topical use in dermatology.
EGCG
Epigallocatechin-3-gallate
cosmetic
dermatology
interaction
stability
Journal
Phytotherapy research : PTR
ISSN: 1099-1573
Titre abrégé: Phytother Res
Pays: England
ID NLM: 8904486
Informations de publication
Date de publication:
Sep 2020
Sep 2020
Historique:
received:
05
12
2019
revised:
08
02
2020
accepted:
01
03
2020
pubmed:
20
3
2020
medline:
24
10
2020
entrez:
20
3
2020
Statut:
ppublish
Résumé
The purpose of this review is to examine epigallocatechin-3-gallate (EGCG) regarding its stability in different conditions (pH-value, concentration, temperature), its interactions with common cosmetic ingredients, and its application in the dermatological field. The literature research considered published journal articles (clinical trials and scientific reviews). Studies were identified by searching electronic databases (MEDLINE and PubMed) and reference lists of respective articles. Higher concentrations of EGCG were reported to correlate with better stability and the same can be said for low temperatures and pH values. The interaction between EGCG and hyaluronic acid strengthens its antioxidant activities. Titanium dioxide coated with EGCG proved a suitable ingredient in sunscreens. The polyphenol possesses antioxidant properties, which proved effective in the prevention of UV-induced skin damage and to alleviate the symptoms of Imiquimod-induced psoriasis. The three endpoints of this review not only showed interesting results but also highlighted some limitations of EGCG. Studies show that the molecule is unstable, which may hinder its dermatological and cosmetic applications. The reported interactions with cosmetic ingredients were limited. As the health aspects of EGCG are well-reported, ECGC has become a focus of interest for health professionals trying to treat common dermatological diseases.
Substances chimiques
Antioxidants
0
Cosmetics
0
Plant Extracts
0
Tea
0
Catechin
8R1V1STN48
epigallocatechin gallate
BQM438CTEL
Imiquimod
P1QW714R7M
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
2170-2179Informations de copyright
© 2020 The Authors. Phytotherapy Research published by John Wiley & Sons Ltd.
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