Regional variation in paraspinal muscle composition using chemical shift encoding-based water-fat MRI.

Muscular fat deposition paraspinal musculature proton density fat fraction (PDFF) quantitative imaging spine

Journal

Quantitative imaging in medicine and surgery
ISSN: 2223-4292
Titre abrégé: Quant Imaging Med Surg
Pays: China
ID NLM: 101577942

Informations de publication

Date de publication:
Feb 2020
Historique:
entrez: 20 3 2020
pubmed: 20 3 2020
medline: 20 3 2020
Statut: ppublish

Résumé

Paraspinal musculature forms one of the largest muscle compartments of the human body, but evidence for regional variation of its composition and dependency on gender or body mass index (BMI) is scarce. This study applied six-echo chemical shift encoding-based water-fat magnetic resonance imaging (MRI) at 3 Tesla in 76 subjects (24 males and 52 females, age: 40.0±13.7 years, BMI: 25.4±5.6 kg/m For the psoas muscles and the erector spinae muscles (L3-L5), gender differences in PDFF values were observed (PDFF psoas muscles: males: 5.1%±3.4% This study explored regional variation of paraspinal muscle composition and dependency on gender and BMI, thus offering new insights into muscle physiology. The PDFF of the erector spinae muscles (L3-L5) was independent of BMI, suggesting that this level may be suited for representative paraspinal muscle segmentation and PDFF extraction as a biomarker for muscle alterations in the future.

Sections du résumé

BACKGROUND BACKGROUND
Paraspinal musculature forms one of the largest muscle compartments of the human body, but evidence for regional variation of its composition and dependency on gender or body mass index (BMI) is scarce.
METHODS METHODS
This study applied six-echo chemical shift encoding-based water-fat magnetic resonance imaging (MRI) at 3 Tesla in 76 subjects (24 males and 52 females, age: 40.0±13.7 years, BMI: 25.4±5.6 kg/m
RESULTS RESULTS
For the psoas muscles and the erector spinae muscles (L3-L5), gender differences in PDFF values were observed (PDFF psoas muscles: males: 5.1%±3.4%
CONCLUSIONS CONCLUSIONS
This study explored regional variation of paraspinal muscle composition and dependency on gender and BMI, thus offering new insights into muscle physiology. The PDFF of the erector spinae muscles (L3-L5) was independent of BMI, suggesting that this level may be suited for representative paraspinal muscle segmentation and PDFF extraction as a biomarker for muscle alterations in the future.

Identifiants

pubmed: 32190574
doi: 10.21037/qims.2020.01.10
pii: qims-10-02-496
pmc: PMC7063279
doi:

Types de publication

Journal Article

Langues

eng

Pagination

496-507

Informations de copyright

2020 Quantitative Imaging in Medicine and Surgery. All rights reserved.

Déclaration de conflit d'intérêts

Conflicts of Interest: The authors have no conflicts of interest to declare.

Références

Front Endocrinol (Lausanne). 2018 Apr 04;9:141
pubmed: 29670577
Neurology. 2014 Sep 23;83(13):1178-83
pubmed: 25142899
PLoS One. 2014 Jan 14;9(1):e85416
pubmed: 24454861
Skeletal Radiol. 2018 Jul;47(7):955-961
pubmed: 29379999
BMC Musculoskelet Disord. 2017 Apr 20;18(1):167
pubmed: 28427393
Front Endocrinol (Lausanne). 2018 Sep 28;9:563
pubmed: 30323789
Spine (Phila Pa 1976). 2017 Apr 15;42(8):616-623
pubmed: 27517512
J Magn Reson Imaging. 2012 Apr;35(4):899-907
pubmed: 22127958
Endocr Rev. 2000 Dec;21(6):697-738
pubmed: 11133069
Eur J Radiol. 2016 Aug;85(8):1512-8
pubmed: 26905521
Curr Opin Endocrinol Diabetes Obes. 2017 Oct;24(5):310-314
pubmed: 28696961
J Gerontol A Biol Sci Med Sci. 2005 Jul;60(7):882-7
pubmed: 16079212
J Magn Reson Imaging. 2017 Jan;45(1):66-73
pubmed: 27341545
MAGMA. 2017 Oct;30(5):449-460
pubmed: 28382554
Lancet Diabetes Endocrinol. 2016 Feb;4(2):174-86
pubmed: 26654575
J Bone Metab. 2013 Nov;20(2):75-81
pubmed: 24524061
J Magn Reson Imaging. 2001 Feb;13(2):263-8
pubmed: 11169833
Circulation. 2012 Jul 3;126(1):126-32
pubmed: 22753534
BMC Musculoskelet Disord. 2017 Jan 19;18(1):25
pubmed: 28103921
Magn Reson Med. 2007 Aug;58(2):354-64
pubmed: 17654578
J Clin Densitom. 2013 Oct-Dec;16(4):508-19
pubmed: 24183640
Nutr Metab (Lond). 2004 Nov 05;1(1):12
pubmed: 15530168
Muscle Nerve. 2014 Aug;50(2):170-6
pubmed: 24677256
Radiology. 2013 Feb;266(2):555-63
pubmed: 23143025
NMR Biomed. 2013 Dec;26(12):1609-29
pubmed: 24123229
Magn Reson Med. 2008 Nov;60(5):1122-34
pubmed: 18956464
Spine J. 2015 Jul 01;15(7):1593-601
pubmed: 25828477
J Obes. 2013;2013:298675
pubmed: 23606951
J Magn Reson Imaging. 2012 Nov;36(5):1011-4
pubmed: 22777847
Spine (Phila Pa 1976). 2006 Aug 1;31(17):1888-99
pubmed: 16924205
Obes Rev. 2010 Jan;11(1):11-8
pubmed: 19656312
Magn Reson Med. 2010 Sep;64(3):811-22
pubmed: 20593375
Radiology. 2015 May;275(2):570-8
pubmed: 25575118
Nutrients. 2018 Dec 13;10(12):
pubmed: 30551614
Spine (Phila Pa 1976). 2015 Jun 15;40(12):E694-700
pubmed: 25785961
Osteoarthritis Cartilage. 2014 Feb;22(2):226-34
pubmed: 24361743
Magn Reson Med. 2011 Nov;66(5):1312-26
pubmed: 21452279
Osteoporos Int. 1995;5(4):262-70
pubmed: 7492865
Endocr Rev. 2006 Dec;27(7):750-61
pubmed: 17122359
Eur Radiol. 2019 Feb;29(2):599-608
pubmed: 30014202
Ann N Y Acad Sci. 2015 Sep;1353:41-59
pubmed: 26250623
AJNR Am J Neuroradiol. 2016 Apr;37(4):742-8
pubmed: 26635285
Eur Radiol. 2019 Sep;29(9):4999-5006
pubmed: 30847590
Eur J Radiol. 2013 Nov;82(11):e697-702
pubmed: 23938236

Auteurs

Nico Sollmann (N)

Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Agnes Zoffl (A)

Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Daniela Franz (D)

Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Jan Syväri (J)

Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Michael Dieckmeyer (M)

Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Egon Burian (E)

Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Elisabeth Klupp (E)

Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Dennis M Hedderich (DM)

Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Christina Holzapfel (C)

Institute for Nutritional Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Theresa Drabsch (T)

Institute for Nutritional Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Jan S Kirschke (JS)

Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Ernst J Rummeny (EJ)

Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Claus Zimmer (C)

Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Hans Hauner (H)

Institute for Nutritional Medicine, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Dimitrios C Karampinos (DC)

Department of Diagnostic and Interventional Radiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Thomas Baum (T)

Department of Diagnostic and Interventional Neuroradiology, Klinikum rechts der Isar, Technische Universität München, Munich, Germany.

Classifications MeSH