Is it or is it not? Lessons learned from a case of suspected vaccine strain measles.


Journal

Australian and New Zealand journal of public health
ISSN: 1753-6405
Titre abrégé: Aust N Z J Public Health
Pays: United States
ID NLM: 9611095

Informations de publication

Date de publication:
Apr 2020
Historique:
received: 01 07 2019
revised: 01 11 2019
accepted: 01 12 2019
pubmed: 20 3 2020
medline: 11 6 2020
entrez: 20 3 2020
Statut: ppublish

Résumé

Measles continues to be a threat to Australia. While post-eradication risks are low, imported measles cases from overseas travellers who are non-immune can cause small outbreaks. This case report discusses the challenge of identifying wild-type measles in an individual who was recently vaccinated with measles-containing vaccine (MCV). A positive polymerase chain reaction (PCR) result for measles for an adult who had recently received a measles-containing vaccine was notified. Investigation revealed no known epidemiological link, recent overseas travel or contact with recent measles cases during the incubation period. The results of the initial sequencing to distinguish between wild-type and vaccine-strain measles were inconclusive. A decision was made to re-run the genotyping, collect additional specimens and quarantine the case until a definitive result was obtained. Sequencing and genotyping revealed that this indeed was a wild-type measles strain. Changing epidemiology of measles means distinguishing between wild-type and vaccine-strain measles has become a new challenge. Implications for public health: The reflection of the public health management of this case has provided a valuable teaching tool for public health professionals globally, particularly in low incidence measles countries.

Identifiants

pubmed: 32190947
doi: 10.1111/1753-6405.12969
doi:

Substances chimiques

Measles Vaccine 0

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

160-162

Informations de copyright

© 2020 The Authors.

Références

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Auteurs

Heidi Lord (H)

Centre for Research in Nursing and Health, South Eastern Sydney Local Health District, New South Wales.

Jen Kok (J)

Centre for Infectious Diseases and Microbiology Laboratory Services, NSW Health Pathology-Institute of Clinical Pathology and Medical Research, New South Wales.

Stephanie Fletcher (S)

Public Health Unit, South Western Sydney Local Health District, New South Wales.

Kate Alexander (K)

Public Health Unit, South Western Sydney Local Health District, New South Wales.

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