Interspecific and intraspecific venom enzymatic variation among cobras (Naja sp. and Ophiophagus hannah).

Acetylcholinesterase / metabolism Africa Animals Antivenins / metabolism Asia Elapid Venoms / enzymology Elapidae / classification Phospholipases A2 / metabolism Proteome / metabolism Species Specificity
Elapidae Enzymology Naja Ophiophagus Proteome Venom variation

Journal

Comparative biochemistry and physiology. Toxicology & pharmacology : CBP
ISSN: 1532-0456
Titre abrégé: Comp Biochem Physiol C Toxicol Pharmacol
Pays: United States
ID NLM: 100959500

Informations de publication

Date de publication:
Jun 2020
Historique:
received: 14 09 2019
revised: 28 02 2020
accepted: 10 03 2020
pubmed: 21 3 2020
medline: 30 1 2021
entrez: 21 3 2020
Statut: ppublish

Résumé

The genera Ophiophagus and Naja comprise part of a clade of snakes referred to as cobras, dangerously venomous front-fanged snakes in the family Elapidae responsible for significant human mortality and morbidity throughout Asia and Africa. We evaluated venom enzyme variation for eleven cobra species and three N. kaouthia populations using SDS-PAGE venom fingerprinting and numerous enzyme assays. Acetylcholinesterase and PLA

Identifiants

DOI: 10.1016/j.cbpc.2020.108743 PMID: 32194156
pubmed: 32194156
pii: S1532-0456(20)30043-0
doi: 10.1016/j.cbpc.2020.108743
pii:
doi:

Substances chimiques

Antivenins 0
Elapid Venoms 0
Proteome 0
Phospholipases A2 EC 3.1.1.4
Acetylcholinesterase EC 3.1.1.7

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

108743

Informations de copyright

Copyright © 2020. Published by Elsevier Inc.

Déclaration de conflit d'intérêts

Declaration of competing interest The authors declare that they have no conflict of interest associated with this manuscript.

Auteurs

Cassandra M Modahl (CM)

School of Biological Sciences, University of Northern Colorado, 501 20th St., Greeley, CO 80639-0017, USA; Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, 117543, Singapore.

Amir Roointan (A)

Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, 117543, Singapore; Regenerative Medicine Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.

Jessica Rogers (J)

School of Biological Sciences, University of Northern Colorado, 501 20th St., Greeley, CO 80639-0017, USA.

Katelyn Currier (K)

School of Biological Sciences, University of Northern Colorado, 501 20th St., Greeley, CO 80639-0017, USA.

Stephen P Mackessy (SP)

School of Biological Sciences, University of Northern Colorado, 501 20th St., Greeley, CO 80639-0017, USA. Electronic address: stephen.mackessy@unco.edu.

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Esterases › Carboxylic ester hydrolases › Cholinesterases › Acetylcholinesterase › Interspecific and intraspecific venom...
questionsmedicales.fr › Régions géographiques › Afrique › Interspecific and intraspecific venom...
questionsmedicales.fr › Eucaryotes › Animaux › Interspecific and intraspecific venom...
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Sérums immuns › Antitoxines › Sérums antivenimeux › Interspecific and intraspecific venom...
questionsmedicales.fr › Régions géographiques › Asie › Interspecific and intraspecific venom...
questionsmedicales.fr › Facteurs biologiques › Toxines biologiques › Venins › Venins de serpent › Venins des élapidés › Interspecific and intraspecific venom...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Reptiles › Serpents › Alethinophidia › Elapidae › Interspecific and intraspecific venom...
questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Hydrolases › Esterases › Carboxylic ester hydrolases › Phospholipases A › Phospholipases A2 › Interspecific and intraspecific venom...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéome › Interspecific and intraspecific venom...
questionsmedicales.fr › Phénomènes biologiques › Spécificité d'espèce › Interspecific and intraspecific venom...