Repeated Application of Transcranial Diagnostic Ultrasound Towards the Visual Cortex Induced Illusory Visual Percepts in Healthy Participants.
diagnostic ultrasound
increased sensitivity
transcranial magnetic stimulation
ultrasound stimulation
visual stimulation
Journal
Frontiers in human neuroscience
ISSN: 1662-5161
Titre abrégé: Front Hum Neurosci
Pays: Switzerland
ID NLM: 101477954
Informations de publication
Date de publication:
2020
2020
Historique:
received:
26
09
2019
accepted:
12
02
2020
entrez:
21
3
2020
pubmed:
21
3
2020
medline:
21
3
2020
Statut:
epublish
Résumé
Transcranial magnetic stimulation (TMS) of the visual cortex can induce phosphenes as participants look at a visual target. So can non-diagnostic ultrasound (nDU), delivered in a transcranial fashion, while participants have closed their eyes during stimulation. Here, we sought to determine if DU, aimed at the visual cortex, could alter the perception of a visual target. We applied a randomized series of actual or sham DU, transcranially and towards the visual cortex of healthy participants while they stared at a visual target (a white crosshair on a light-blue background), with the ultrasound device placed where TMS elicited phosphenes. These participants observed percepts seven out of ten times, which consisted of extra or extensions of lines relative to the original crosshair, and additional colors, an average of 53.7 ± 2.6% of the time over the course of the experiment. Seven out of ten different participants exposed to
Identifiants
pubmed: 32194387
doi: 10.3389/fnhum.2020.00066
pmc: PMC7062642
doi:
Types de publication
Journal Article
Langues
eng
Pagination
66Subventions
Organisme : NEI NIH HHS
ID : R21 EY027557
Pays : United States
Informations de copyright
Copyright © 2020 Schimek, Burke-Conte, Abernethy, Schimek, Burke-Conte, Bobola, Stocco and Mourad.
Références
PLoS One. 2008;3(10):e3511
pubmed: 18958151
Brain Stimul. 2014 Sep-Oct;7(5):748-56
pubmed: 25088462
J Physiol. 2010 Jul 1;588(Pt 13):2291-304
pubmed: 20478978
Nat Neurosci. 2014 Feb;17(2):322-9
pubmed: 24413698
Sci Rep. 2015 Mar 04;5:8743
pubmed: 25735418
Ultrasound Med Biol. 2019 Jul;45(7):1509-1536
pubmed: 31109842
Nat Rev Neurosci. 2013 May;14(5):350-63
pubmed: 23595013
Curr Biol. 2013 Dec 2;23(23):2430-3
pubmed: 24239121
Int J Imaging Syst Technol. 2018 Jun;28(2):106-112
pubmed: 29861548
Nano Lett. 2017 Feb 8;17(2):652-659
pubmed: 28094959
PLoS One. 2014 Feb 04;9(2):e86939
pubmed: 24504255
Neuron. 2010 Jun 10;66(5):681-94
pubmed: 20547127
PLoS One. 2015 Sep 23;10(9):e0137303
pubmed: 26398267
Neuron. 2019 Mar 20;101(6):1109-1116.e5
pubmed: 30765166
Ultrasound Med Biol. 2016 Jul;42(7):1512-30
pubmed: 27090861
J Ther Ultrasound. 2018 Dec 10;6:11
pubmed: 30555696
Science. 2014 Aug 8;345(6197):660-5
pubmed: 25104383
Ultrasound Med Biol. 2016 Feb;42(2):459-70
pubmed: 26525652
Brain Stimul. 2014 Nov-Dec;7(6):900-8
pubmed: 25265863
BMC Neurosci. 2011 Mar 06;12:23
pubmed: 21375781
Science. 1955 Sep 16;122(3168):517-8
pubmed: 13255886
Sci Rep. 2019 Apr 16;9(1):6115
pubmed: 30992474
Curr Pain Headache Rep. 2018 Jul 10;22(9):60
pubmed: 29987680
Phys Life Rev. 2010 Sep;7(3):269-84
pubmed: 20447880
Neurosci Behav Physiol. 1988 Sep-Oct;18(5):369-75
pubmed: 3063995
Elife. 2019 Feb 12;8:
pubmed: 30747105
Brain Stimul. 2017 Nov - Dec;10(6):1024-1031
pubmed: 28789857
Ultrasound Med Biol. 2016 Dec;42(12):2950-2956
pubmed: 27658751
Neuroscientist. 2011 Feb;17(1):37-53
pubmed: 21343407
Sci Rep. 2016 Sep 23;6:34026
pubmed: 27658372
Brain Stimul. 2016 Nov - Dec;9(6):940-941
pubmed: 27567470
Stat Med. 2004 Mar 30;23(6):859-74; discussion 875-7,879-80
pubmed: 15027075
Front Neurol. 2018 Nov 28;9:1007
pubmed: 30546342
Ultrasound Med Biol. 2012 Sep;38(9):1568-75
pubmed: 22763009
Neuroreport. 2011 Oct 26;22(15):783-7
pubmed: 21876461
Med Phys. 2013 Aug;40(8):082902
pubmed: 23927357
Med Phys. 2016 Oct;43(10):5730
pubmed: 27782686
Brain Stimul. 2013 May;6(3):409-15
pubmed: 22664271
Ultrasound Med Biol. 2013 Feb;39(2):312-31
pubmed: 23219040
J Neurosurg. 2018 Mar;128(3):875-884
pubmed: 28430035
Neuroimage. 2011 Jun 1;56(3):1267-75
pubmed: 21354315
Neuroimage. 2008 Aug 1;42(1):379-84
pubmed: 18511301