Comparison of preoxygenation with a high-flow nasal cannula and a simple mask before intubation during induction of general anesthesia in patients undergoing head and neck surgery: Study protocol clinical trial (SPIRIT Compliant).
Anesthesia, General
/ trends
Blood Gas Analysis
Blood Gas Monitoring, Transcutaneous
/ methods
Cannula
/ standards
Head
/ surgery
Humans
Hyperbaric Oxygenation
/ trends
Intubation, Intratracheal
/ methods
Masks
/ standards
Neck
/ surgery
Noninvasive Ventilation
/ instrumentation
Oxygen
/ blood
Prospective Studies
Radial Artery
/ surgery
Respiration, Artificial
/ instrumentation
Vascular Access Devices
/ standards
Journal
Medicine
ISSN: 1536-5964
Titre abrégé: Medicine (Baltimore)
Pays: United States
ID NLM: 2985248R
Informations de publication
Date de publication:
Mar 2020
Mar 2020
Historique:
entrez:
21
3
2020
pubmed:
21
3
2020
medline:
28
3
2020
Statut:
ppublish
Résumé
To assess the arterial oxygen partial pressure (PaO2) at defined time points during preoxygenation and to compare high-flow heated humidified nasal oxygenation with standard preoxygenation using oxygen insufflation via a facemask for at least 5 minutes, before intubation during induction of general anesthesia. This randomized, single-blinded, prospective study will be conducted in patients undergoing head and neck surgery. After standard monitoring, the artery catheter at the radial artery or dorsalis pedis artery will be placed and arterial blood gas analysis (ABGA) for baseline values will be performed simultaneously. Each group will be subjected to 1 of 2 preoxygenation methods (high-flow nasal cannula or simple facemask) for 5 minutes, and ABGA will be performed twice. After confirming intubation, we will start mechanical ventilation and check the vital signs and perform the final ABGA. This trial aims to examine the trajectory of PaO2 levels during the whole preoxygenation procedure and after intubation. We hypothesize that preoxygenation with the high-flow nasal cannula will be superior to that with the face mask. This trial was registered with the Clinical Trial Registry (NCT03896906; ClinicalTrials.gov).
Sections du résumé
BACKGROUND
BACKGROUND
To assess the arterial oxygen partial pressure (PaO2) at defined time points during preoxygenation and to compare high-flow heated humidified nasal oxygenation with standard preoxygenation using oxygen insufflation via a facemask for at least 5 minutes, before intubation during induction of general anesthesia.
METHODS
METHODS
This randomized, single-blinded, prospective study will be conducted in patients undergoing head and neck surgery. After standard monitoring, the artery catheter at the radial artery or dorsalis pedis artery will be placed and arterial blood gas analysis (ABGA) for baseline values will be performed simultaneously. Each group will be subjected to 1 of 2 preoxygenation methods (high-flow nasal cannula or simple facemask) for 5 minutes, and ABGA will be performed twice. After confirming intubation, we will start mechanical ventilation and check the vital signs and perform the final ABGA.
DISCUSSION
CONCLUSIONS
This trial aims to examine the trajectory of PaO2 levels during the whole preoxygenation procedure and after intubation. We hypothesize that preoxygenation with the high-flow nasal cannula will be superior to that with the face mask.
STUDY REGISTRATION
BACKGROUND
This trial was registered with the Clinical Trial Registry (NCT03896906; ClinicalTrials.gov).
Identifiants
pubmed: 32195955
doi: 10.1097/MD.0000000000019525
pii: 00005792-202003200-00033
pmc: PMC7220443
doi:
Substances chimiques
Oxygen
S88TT14065
Banques de données
ClinicalTrials.gov
['NCT03896906']
Types de publication
Comparative Study
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
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