Potential Protection Against Type 2 Diabetes in Obesity Through Lower CD36 Expression and Improved Exocytosis in β-Cells.


Journal

Diabetes
ISSN: 1939-327X
Titre abrégé: Diabetes
Pays: United States
ID NLM: 0372763

Informations de publication

Date de publication:
06 2020
Historique:
received: 19 09 2019
accepted: 09 03 2020
pubmed: 22 3 2020
medline: 23 10 2020
entrez: 22 3 2020
Statut: ppublish

Résumé

Obesity is a risk factor for type 2 diabetes (T2D); however, not all obese individuals develop the disease. In this study, we aimed to investigate the cause of differential insulin secretion capacity of pancreatic islets from donors with T2D and non-T2D (ND), especially obese donors (BMI ≥30 kg/m

Identifiants

pubmed: 32198214
pii: db19-0944
doi: 10.2337/db19-0944
pmc: PMC7243297
doi:

Substances chimiques

Antibodies 0
CD36 Antigens 0
Insulin 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

1193-1205

Commentaires et corrections

Type : CommentIn

Informations de copyright

© 2020 by the American Diabetes Association.

Références

PLoS One. 2012;7(10):e47381
pubmed: 23077605
Diabetes. 1999 Sep;48(9):1686-90
pubmed: 10480595
Proc Natl Acad Sci U S A. 2014 Sep 23;111(38):13924-9
pubmed: 25201977
Annu Rev Nutr. 2008;28:233-51
pubmed: 18481923
Science. 2016 Oct 7;354(6308):69-73
pubmed: 27846494
PLoS One. 2015 Mar 24;10(3):e0120879
pubmed: 25803449
J Biol Chem. 2003 Mar 21;278(12):10297-303
pubmed: 12525490
Cell Metab. 2009 Dec;10(6):455-65
pubmed: 19945403
Cell Metab. 2007 Oct;6(4):267-79
pubmed: 17908556
Endocrinology. 2016 Feb;157(2):570-85
pubmed: 26650570
Nat Rev Endocrinol. 2013 Oct;9(10):615-23
pubmed: 23959366
Nature. 2017 Jan 5;541(7635):41-45
pubmed: 27974793
J Intern Med. 2013 Jul;274(1):25-40
pubmed: 23551521
Cell Metab. 2007 Oct;6(4):320-8
pubmed: 17908560
Mol Cell Endocrinol. 2012 Nov 25;364(1-2):36-45
pubmed: 22939844
J Biol Chem. 2011 Apr 15;286(15):13647-56
pubmed: 21335550
Diabetes. 2005 Feb;54(2):472-81
pubmed: 15677505
Cell Metab. 2018 Feb 6;27(2):470-478.e4
pubmed: 29414688
J Diabetes Investig. 2011 Apr 7;2(2):82-91
pubmed: 24843466
Crit Rev Food Sci Nutr. 2017 May 24;57(8):1673-1680
pubmed: 26147190
Mol Metab. 2018 Feb;8:144-157
pubmed: 29307512
Diabetes Obes Metab. 2012 Oct;14 Suppl 3:152-60
pubmed: 22928576
Diabetologia. 2007 Apr;50(4):752-63
pubmed: 17268797
Diabetes. 1995 Aug;44(8):863-70
pubmed: 7621989
Nat Rev Mol Cell Biol. 2018 Jan;19(1):31-44
pubmed: 28974775
J Mol Endocrinol. 2006 Jun;36(3):503-15
pubmed: 16720719
Pflugers Arch. 2002 May;444(1-2):43-51
pubmed: 11976915
Endocr Rev. 2008 May;29(3):351-66
pubmed: 18048763
Clin Lipidol. 2013 Dec;8(6):659-667
pubmed: 24533033
Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):8919-24
pubmed: 22566644
Diabetologia. 2012 Oct;55(10):2565-2582
pubmed: 22869320
J Clin Invest. 2011 Sep;121(9):3589-97
pubmed: 21865645
Cell. 1999 Feb 5;96(3):329-39
pubmed: 10025399
Diabetologia. 2003 Aug;46(8):1029-45
pubmed: 12879249
Biochim Biophys Acta. 2010 Feb;1801(2):191-7
pubmed: 19931418
Cell Metab. 2010 Dec 1;12(6):619-32
pubmed: 21109194
Biochemistry. 1997 Oct 21;36(42):12939-47
pubmed: 9335553
Front Endocrinol (Lausanne). 2018 Jul 16;9:384
pubmed: 30061862
J Biol Chem. 2002 Dec 13;277(50):48115-21
pubmed: 12351658
J Biol Chem. 1999 Sep 17;274(38):26761-6
pubmed: 10480880
Biochim Biophys Acta. 2015 Nov;1852(11):2414-22
pubmed: 26297980
Physiol Behav. 2011 Nov 30;105(1):36-42
pubmed: 21354192
Cell Metab. 2006 Aug;4(2):143-54
pubmed: 16890542
Diabetes. 2012 Jul;61(7):1726-33
pubmed: 22492527
Diabetes. 2008 Jul;57(7):1774-83
pubmed: 18586909
Cell Transplant. 2018 Jul;27(7):1031-1038
pubmed: 29945463
Physiol Rep. 2017 Nov;5(21):
pubmed: 29122960
Diabetes. 2009 Dec;58(12):2718-25
pubmed: 19940235
Diabetes. 2010 Jan;59(1):119-27
pubmed: 19826167
Diabetes. 2006 Feb;55(2):435-40
pubmed: 16443778
Endocrinology. 1999 Aug;140(8):3422-8
pubmed: 10433196
Diabetes. 2013 Jul;62(7):2157-63
pubmed: 23801714

Auteurs

Mototsugu Nagao (M)

Department of Clinical Sciences, Malmö, Islet Cell Exocytosis, Lund University Diabetes Centre, Lund University, Clinical Research Centre, Malmö, Sweden lena.eliasson@med.lu.se s8067@nms.ac.jp.
Department of Endocrinology, Diabetes and Metabolism, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.

Jonathan L S Esguerra (JLS)

Department of Clinical Sciences, Malmö, Islet Cell Exocytosis, Lund University Diabetes Centre, Lund University, Clinical Research Centre, Malmö, Sweden.

Akira Asai (A)

Department of Clinical Sciences, Malmö, Islet Cell Exocytosis, Lund University Diabetes Centre, Lund University, Clinical Research Centre, Malmö, Sweden.
Department of Endocrinology, Diabetes and Metabolism, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.
Food and Health Science Research Unit, Graduate School of Agricultural Science, Tohoku University, Sendai, Japan.

Jones K Ofori (JK)

Department of Clinical Sciences, Malmö, Islet Cell Exocytosis, Lund University Diabetes Centre, Lund University, Clinical Research Centre, Malmö, Sweden.

Anna Edlund (A)

Department of Clinical Sciences, Malmö, Islet Cell Exocytosis, Lund University Diabetes Centre, Lund University, Clinical Research Centre, Malmö, Sweden.

Anna Wendt (A)

Department of Clinical Sciences, Malmö, Islet Cell Exocytosis, Lund University Diabetes Centre, Lund University, Clinical Research Centre, Malmö, Sweden.

Hitoshi Sugihara (H)

Department of Endocrinology, Diabetes and Metabolism, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.

Claes B Wollheim (CB)

Department of Cell Physiology and Metabolism, Faculty of Medicine, University of Geneva, Geneva, Switzerland.

Shinichi Oikawa (S)

Department of Endocrinology, Diabetes and Metabolism, Graduate School of Medicine, Nippon Medical School, Tokyo, Japan.

Lena Eliasson (L)

Department of Clinical Sciences, Malmö, Islet Cell Exocytosis, Lund University Diabetes Centre, Lund University, Clinical Research Centre, Malmö, Sweden lena.eliasson@med.lu.se s8067@nms.ac.jp.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH