Repression of the Type I Interferon Pathway Underlies MYC- and KRAS-Dependent Evasion of NK and B Cells in Pancreatic Ductal Adenocarcinoma.
Journal
Cancer discovery
ISSN: 2159-8290
Titre abrégé: Cancer Discov
Pays: United States
ID NLM: 101561693
Informations de publication
Date de publication:
06 2020
06 2020
Historique:
received:
30
05
2019
revised:
07
02
2020
accepted:
18
03
2020
pubmed:
23
3
2020
medline:
1
10
2021
entrez:
23
3
2020
Statut:
ppublish
Résumé
MYC is implicated in the development and progression of pancreatic cancer, yet the precise level of MYC deregulation required to contribute to tumor development has been difficult to define. We used modestly elevated expression of human MYC, driven from the
Identifiants
pubmed: 32200350
pii: 2159-8290.CD-19-0620
doi: 10.1158/2159-8290.CD-19-0620
pmc: PMC7611248
mid: EMS128842
doi:
Substances chimiques
Interferon Type I
0
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
872-887Subventions
Organisme : Wellcome Trust
ID : 105614/Z/14/Z
Pays : United Kingdom
Organisme : Cancer Research UK
ID : A17196
Pays : United Kingdom
Organisme : Cancer Research UK
ID : A21139
Pays : United Kingdom
Organisme : Cancer Research UK
ID : A23983
Pays : United Kingdom
Organisme : Wellcome Trust
ID : 105614
Pays : United Kingdom
Organisme : Cancer Research UK
ID : A25142
Pays : United Kingdom
Organisme : Wellcome Trust
Pays : United Kingdom
Organisme : Worldwide Cancer Research
ID : 15-0279
Pays : United Kingdom
Informations de copyright
©2020 American Association for Cancer Research.
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