Visual memory and psychotic symptoms in youth.


Journal

Cognitive neuropsychiatry
ISSN: 1464-0619
Titre abrégé: Cogn Neuropsychiatry
Pays: England
ID NLM: 9713497

Informations de publication

Date de publication:
05 2020
Historique:
pubmed: 24 3 2020
medline: 30 12 2020
entrez: 24 3 2020
Statut: ppublish

Résumé

Psychotic symptoms are common during childhood and adolescence and may indicate transdiagnostic risk of future psychiatric disorders. Lower visual memory ability has been suggested as a potential indicator of future risk of mental illness. The relationship between visual memory and clinician-confirmed definite psychotic symptoms in youth has not yet been explored. We examined visual memory and psychotic symptoms among 205 participants aged 7-27 years in a cohort enriched for parental mood and psychotic disorders. We assessed visual memory using the Rey Complex Figure Test (RCFT) and psychotic symptoms using validated semi-structured interview measures. We tested the relationship between visual memory and psychotic symptoms using mixed-effects logistic regression. After accounting for age, sex, and family clustering, we found that psychotic symptoms were significantly associated with lower visual memory (OR = 1.80, 95% CI 1.06-3.06, Lower visual memory performance is associated with psychotic symptoms among youth, regardless of general cognitive ability. This finding may inform future targeted early interventions.

Sections du résumé

BACKGROUND
Psychotic symptoms are common during childhood and adolescence and may indicate transdiagnostic risk of future psychiatric disorders. Lower visual memory ability has been suggested as a potential indicator of future risk of mental illness. The relationship between visual memory and clinician-confirmed definite psychotic symptoms in youth has not yet been explored.
METHODS
We examined visual memory and psychotic symptoms among 205 participants aged 7-27 years in a cohort enriched for parental mood and psychotic disorders. We assessed visual memory using the Rey Complex Figure Test (RCFT) and psychotic symptoms using validated semi-structured interview measures. We tested the relationship between visual memory and psychotic symptoms using mixed-effects logistic regression.
RESULTS
After accounting for age, sex, and family clustering, we found that psychotic symptoms were significantly associated with lower visual memory (OR = 1.80, 95% CI 1.06-3.06,
CONCLUSION
Lower visual memory performance is associated with psychotic symptoms among youth, regardless of general cognitive ability. This finding may inform future targeted early interventions.

Identifiants

pubmed: 32200701
doi: 10.1080/13546805.2020.1741342
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

231-241

Subventions

Organisme : CIHR
ID : 124976
Pays : Canada
Organisme : CIHR
ID : 142738
Pays : Canada
Organisme : CIHR
ID : 148394
Pays : Canada
Organisme : CIHR
ID : 157975
Pays : Canada

Auteurs

Emily Howes Vallis (E)

Department of Psychiatry, Dalhousie University, Halifax, Canada.
Nova Scotia Health Authority, Halifax, Canada.

Lynn E MacKenzie (LE)

Department of Psychiatry, Dalhousie University, Halifax, Canada.
Department of Psychology and Neuroscience, Dalhousie University, Halifax, Canada.

Alyson Zwicker (A)

Nova Scotia Health Authority, Halifax, Canada.
Department of Pathology, Dalhousie University, Halifax, Canada.

Vladislav Drobinin (V)

Nova Scotia Health Authority, Halifax, Canada.
Department of Medical Neuroscience, Dalhousie University, Halifax, Canada.

Sheri Rempel (S)

Nova Scotia Health Authority, Halifax, Canada.

Sabina Abidi (S)

Department of Psychiatry, Dalhousie University, Halifax, Canada.
IWK Health Centre, Halifax, Canada.

David Lovas (D)

Department of Psychiatry, Dalhousie University, Halifax, Canada.
IWK Health Centre, Halifax, Canada.

Alexa Bagnell (A)

Department of Psychiatry, Dalhousie University, Halifax, Canada.
IWK Health Centre, Halifax, Canada.

Lukas Propper (L)

Department of Psychiatry, Dalhousie University, Halifax, Canada.
IWK Health Centre, Halifax, Canada.

Antonina Omisade (A)

Nova Scotia Health Authority, Halifax, Canada.
Department of Psychology and Neuroscience, Dalhousie University, Halifax, Canada.

Helen L Fisher (HL)

Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

Barbara Pavlova (B)

Department of Psychiatry, Dalhousie University, Halifax, Canada.
Nova Scotia Health Authority, Halifax, Canada.

Rudolf Uher (R)

Department of Psychiatry, Dalhousie University, Halifax, Canada.
Nova Scotia Health Authority, Halifax, Canada.
Department of Psychology and Neuroscience, Dalhousie University, Halifax, Canada.
Department of Pathology, Dalhousie University, Halifax, Canada.
Department of Medical Neuroscience, Dalhousie University, Halifax, Canada.
IWK Health Centre, Halifax, Canada.
Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, UK.

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