The interplay between childhood trauma, cognitive biases, and cannabis use on the risk of psychosis in nonclinical young adults in Poland.
Childhood trauma
cognitive bias
psychotic-like experiences
Journal
European psychiatry : the journal of the Association of European Psychiatrists
ISSN: 1778-3585
Titre abrégé: Eur Psychiatry
Pays: England
ID NLM: 9111820
Informations de publication
Date de publication:
23 03 2020
23 03 2020
Historique:
pubmed:
24
3
2020
medline:
12
1
2021
entrez:
24
3
2020
Statut:
epublish
Résumé
Childhood traumatic events are risk factors for psychotic-like experiences (PLEs). However, the mechanisms explaining how trauma may contribute to the development of PLEs are not fully understood. In our study, we investigated whether cannabis use and cognitive biases mediate the relationship between early trauma and PLEs. A total sample of 6,772 young adults (age 26.6 ± 4.7, 2,181 male and 3,433 female) was recruited from the general population to participate in an online survey. We excluded 1,158 individuals due to a self-reported lifetime diagnosis of any mental disorder. The online survey included selected items from the following questionnaires: Traumatic Experience Checklist (TEC, 3 items), Childhood Experience of Care and Abuse Questionnaire (CECA.Q, 3 items), Cannabis Problems Questionnaire (CPQ, 10 items), Davos Assessment of Cognitive Biases Scale (DACOBS-18, 9 items), and Prodromal Questionnaire-16 (PQ-16). Mediation analyses were performed with respect to different categories of traumatic experiences (emotional, physical and sexual abuse as well as emotional neglect). Our results showed significant associations of any time of childhood trauma with higher scores of cannabis use (CPQ), cognitive biases (DACOBS), and PLEs (PQ-16) (p < 0.001). We found a direct effect of childhood trauma on PLEs as well as significant indirect effect mediated through cannabis use and cognitive biases. All models tested for the effects of specific childhood adversities revealed similar results. The percentage of variance in PQ-16 scores explained by serial mediation models varied between 32.8 and 34.2% depending on childhood trauma category. Cannabis use and cognitive biases play an important mediating role in the relationship between childhood traumatic events and the development of PLEs in a nonclinical young adult population.
Sections du résumé
BACKGROUND
Childhood traumatic events are risk factors for psychotic-like experiences (PLEs). However, the mechanisms explaining how trauma may contribute to the development of PLEs are not fully understood. In our study, we investigated whether cannabis use and cognitive biases mediate the relationship between early trauma and PLEs.
METHODS
A total sample of 6,772 young adults (age 26.6 ± 4.7, 2,181 male and 3,433 female) was recruited from the general population to participate in an online survey. We excluded 1,158 individuals due to a self-reported lifetime diagnosis of any mental disorder. The online survey included selected items from the following questionnaires: Traumatic Experience Checklist (TEC, 3 items), Childhood Experience of Care and Abuse Questionnaire (CECA.Q, 3 items), Cannabis Problems Questionnaire (CPQ, 10 items), Davos Assessment of Cognitive Biases Scale (DACOBS-18, 9 items), and Prodromal Questionnaire-16 (PQ-16). Mediation analyses were performed with respect to different categories of traumatic experiences (emotional, physical and sexual abuse as well as emotional neglect).
RESULTS
Our results showed significant associations of any time of childhood trauma with higher scores of cannabis use (CPQ), cognitive biases (DACOBS), and PLEs (PQ-16) (p < 0.001). We found a direct effect of childhood trauma on PLEs as well as significant indirect effect mediated through cannabis use and cognitive biases. All models tested for the effects of specific childhood adversities revealed similar results. The percentage of variance in PQ-16 scores explained by serial mediation models varied between 32.8 and 34.2% depending on childhood trauma category.
CONCLUSION
Cannabis use and cognitive biases play an important mediating role in the relationship between childhood traumatic events and the development of PLEs in a nonclinical young adult population.
Identifiants
pubmed: 32200775
doi: 10.1192/j.eurpsy.2020.31
pii: S0924933820000310
pmc: PMC7355126
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
e35Références
Schizophr Bull. 2012 Jun;38(4):661-71
pubmed: 22461484
Addiction. 2004 Oct;99(10):1333-41
pubmed: 15369572
Psychiatry Res. 2014 Aug 15;218(1-2):180-6
pubmed: 24745470
Schizophr Bull. 2017 May 1;43(3):644-653
pubmed: 27431873
Psychopharmacology (Berl). 2011 Mar;214(1):107-20
pubmed: 21088961
Psychol Med. 2013 Jul;43(7):1365-76
pubmed: 23084507
Drug Alcohol Depend. 2016 May 1;162:162-9
pubmed: 27012434
Behav Res Methods. 2008 Aug;40(3):879-91
pubmed: 18697684
Psychiatry Res. 2018 Jan;259:571-578
pubmed: 29195191
Addiction. 2012 Feb;107(2):381-7
pubmed: 21851445
Psychol Med. 2009 Feb;39(2):199-209
pubmed: 18588739
Psychol Med. 2014 Jun;44(8):1615-24
pubmed: 24025687
Lancet. 2007 Jul 28;370(9584):319-28
pubmed: 17662880
Schizophr Res. 2019 Apr;206:183-193
pubmed: 30527930
Psychol Med. 2007 Apr;37(4):513-27
pubmed: 17288646
Early Interv Psychiatry. 2018 Dec;12(6):1013-1023
pubmed: 29927066
Psychol Med. 2018 Jul;48(9):1540-1550
pubmed: 29310741
JAMA Psychiatry. 2019 Jan 1;76(1):87-94
pubmed: 30347017
Schizophr Res. 2013 Mar;144(1-3):63-71
pubmed: 23332365
Psychol Addict Behav. 2015 Sep;29(3):633-8
pubmed: 26415060
Schizophr Res Cogn. 2016 May 16;4:18-23
pubmed: 28740809
Schizophr Res. 2019 Apr;206:149-156
pubmed: 30545759
Schizophr Res. 2011 Dec;133(1-3):133-42
pubmed: 21999904
Psychol Med. 2010 Oct;40(10):1627-34
pubmed: 19995476
Psychiatry Res. 2015 Jun 30;227(2-3):144-51
pubmed: 25912376
Eur Psychiatry. 2019 Feb;56:84-90
pubmed: 30599337
Psychol Med. 2009 Feb;39(2):179-95
pubmed: 18606047
Am J Psychiatry. 2003 Jan;160(1):13-23
pubmed: 12505794
Schizophr Res. 2019 Nov;213:56-64
pubmed: 30573409
Psychol Med. 2016 Dec;46(16):3383-3395
pubmed: 27628967
Schizophr Bull. 2015 May;41(3):687-97
pubmed: 25217481
Psychol Med. 2012 Jan;42(1):149-59
pubmed: 21676285
J Trauma Stress. 2016 Oct;29(5):422-429
pubmed: 27622844
Schizophr Bull. 2013 Nov;39(6):1328-36
pubmed: 23236077
Schizophr Bull. 2014 Nov;40(6):1443-51
pubmed: 24399191
Schizophr Res. 2000 Sep 29;45(1-2):11-20
pubmed: 10978868
Aust N Z J Psychiatry. 2016 Mar;50(3):208-19
pubmed: 26286531
Neurosci Biobehav Rev. 2017 Apr;75:393-406
pubmed: 28216171
Addiction. 2013 Apr;108(4):733-40
pubmed: 23216690
Soc Psychiatry Psychiatr Epidemiol. 2002 Dec;37(12):572-9
pubmed: 12545234
Schizophr Res. 2019 Mar;205:15-22
pubmed: 29463456
Schizophr Bull. 2018 Aug 20;44(5):1111-1122
pubmed: 29301025
Drug Alcohol Depend. 2005 Dec 12;80(3):313-9
pubmed: 15916867
Schizophr Res. 2018 Mar;193:218-224
pubmed: 28712969
J Affect Disord. 2019 Jul 1;254:26-33
pubmed: 31082628
Schizophr Bull. 2012 May;38(3):531-42
pubmed: 21030456
J Clin Med. 2019 Aug 15;8(8):
pubmed: 31443188
Early Interv Psychiatry. 2020 Feb;14(1):87-96
pubmed: 31099186
Schizophr Bull. 2012 Nov;38(6):1288-96
pubmed: 22516147
Schizophr Bull. 2008 Mar;34(2):220-5
pubmed: 18203757
Psychol Med. 2013 May;43(5):1033-44
pubmed: 23171473
Psychiatry Res. 2014 Jul 30;217(3):202-9
pubmed: 24726818
Schizophr Res. 2018 Feb;192:317-326
pubmed: 28601498
Schizophr Res. 2015 Feb;161(2-3):496-500
pubmed: 25468176
Psychiatry Res. 2016 Nov 30;245:267-275
pubmed: 27565698
Noro Psikiyatr Ars. 2017 Mar;54(1):38-42
pubmed: 28566957
Br J Psychiatry. 2014;204:346-53
pubmed: 24627297
Dev Psychobiol. 2009 Jul;51(5):408-16
pubmed: 19492313
Am J Psychiatry. 2013 Jul;170(7):734-41
pubmed: 23599019
Early Interv Psychiatry. 2018 Apr;12(2):135-142
pubmed: 26560802
Schizophr Res. 2018 Nov;201:352-359
pubmed: 29743139
World Psychiatry. 2014 Jun;13(2):184-8
pubmed: 24890071
Early Interv Psychiatry. 2019 Aug;13(4):908-913
pubmed: 29968298
Schizophr Bull. 2009 May;35(3):549-62
pubmed: 19325164
Psychol Med. 2020 Jan;50(1):116-124
pubmed: 30626466
J Neurosci. 2015 Jul 15;35(28):10103-11
pubmed: 26180188
Arch Psychol (Chic). 2017 Dec 15;1(3):
pubmed: 29400347
Eur Psychiatry. 2013 May;28(4):207-12
pubmed: 22944339
Psychol Med. 2019 Mar;49(4):628-638
pubmed: 29807550
Clin Psychol Rev. 2017 Jun;54:96-106
pubmed: 28448827
Psychiatr Serv. 2014 Jun 1;65(6):774-80
pubmed: 24534875