SnapShot: Natural Killer Cells.

Animals Cytokines / metabolism Humans Immunity, Innate Immunotherapy, Active / methods Killer Cells, Natural / immunology Mice Neoplasms / immunology

Journal

Cell
ISSN: 1097-4172
Titre abrégé: Cell
Pays: United States
ID NLM: 0413066

Informations de publication

Date de publication:
19 03 2020
Historique:
entrez: 24 3 2020
pubmed: 24 3 2020
medline: 21 10 2020
Statut: ppublish

Résumé

NK cells are broadly distributed innate lymphoid cells (ILCs) encompassing distinct populations based on CD11b and CD27 expression in mice or CD56 intensity in humans. Involved in anti-viral and anti-tumor immunity thanks to their cytokines and chemokines secretion as well as their cytotoxic capabilities, NK cells have emerged as a promising therapeutic target in several solid tumors and hematological malignancies. To view this Snapshot, open or download the PDF.

Identifiants

DOI: 10.1016/j.cell.2020.02.029 PMID: 32200803
pubmed: 32200803
pii: S0092-8674(20)30173-2
doi: 10.1016/j.cell.2020.02.029
pii:
doi:

Substances chimiques

Cytokines 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1280-1280.e1

Informations de copyright

Copyright © 2020 Elsevier Inc. All rights reserved.

Auteurs

Adeline Crinier (A)

Aix Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France.

Emilie Narni-Mancinelli (E)

Aix Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France.

Sophie Ugolini (S)

Aix Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France.

Eric Vivier (E)

Aix Marseille Univ, CNRS, INSERM, Centre d'Immunologie de Marseille-Luminy, Marseille, France; Immunology, Marseille Immunopole, Hôpital de la Timone, Assistance Publique des Hôpitaux de Marseille, France; Innate Pharma Research Laboratories, Innate Pharma, Marseille, France.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › SnapShot: Natural Killer Cells.
questionsmedicales.fr › Facteurs biologiques › Protéines et peptides de signalisation intercellulaire › Cytokines › SnapShot: Natural Killer Cells.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › SnapShot: Natural Killer Cells.
questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immunité innée › SnapShot: Natural Killer Cells.
questionsmedicales.fr › Techniques d'investigation › Techniques immunologiques › Immunothérapie active › SnapShot: Natural Killer Cells.
questionsmedicales.fr › Systèmes sanguin et immunitaire › Système immunitaire › Leucocytes › Agranulocytes › Lymphocytes › Cellules tueuses naturelles › SnapShot: Natural Killer Cells.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › SnapShot: Natural Killer Cells.
questionsmedicales.fr › Tumeurs › SnapShot: Natural Killer Cells.