The role of salivary contents and modern technologies in the remineralization of dental enamel: a review.
Calcium Phosphate
Enamel
Fluoride
Remineralization
Saliva
Journal
F1000Research
ISSN: 2046-1402
Titre abrégé: F1000Res
Pays: England
ID NLM: 101594320
Informations de publication
Date de publication:
2020
2020
Historique:
accepted:
25
02
2020
entrez:
24
3
2020
pubmed:
24
3
2020
medline:
5
2
2021
Statut:
epublish
Résumé
Human enamel once formed cannot be biologically repaired or replaced. Saliva has a significant role in remineralization of dental enamel. It not only has a buffering capacity to neutralize the oral cavity's low pH generated after acidic encounters, but also acts as a carrier of essential ions, such as fluoride, calcium and phosphate, which have a positive role in enamel's remineralization. This review discusses how salivary contents, like proteins and enzymes, have a natural role in enamel's mineralization. In addition, the presence of ions, such as fluoride, calcium and phosphate, in saliva further enhances its capability to remineralize the demineralized enamel surface. The review further examines modern innovative technologies, based on biomimetic regeneration systems, including dentin phosphoproteins, aspartate-serine-serine, recombinant porcine amelogenin, leucine-rich amelogenin peptide and nano-hydroxyapatite, that promote enamel remineralization. Fluoride boosters like calcium phosphates, polyphosphates, and certain natural products can also play an important role in enamel remineralization.
Identifiants
pubmed: 32201577
doi: 10.12688/f1000research.22499.1
pmc: PMC7076334
doi:
Substances chimiques
Ions
0
Phosphates
0
Fluorides
Q80VPU408O
Calcium
SY7Q814VUP
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
171Informations de copyright
Copyright: © 2020 Farooq I and Bugshan A.
Déclaration de conflit d'intérêts
No competing interests were disclosed.
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