Fate of Thymol and Its Monoglucosides in the Gastrointestinal Tract of Piglets.
Journal
ACS omega
ISSN: 2470-1343
Titre abrégé: ACS Omega
Pays: United States
ID NLM: 101691658
Informations de publication
Date de publication:
17 Mar 2020
17 Mar 2020
Historique:
received:
16
12
2019
accepted:
25
02
2020
entrez:
24
3
2020
pubmed:
24
3
2020
medline:
24
3
2020
Statut:
epublish
Résumé
The monoterpene thymol has been proposed as a valuable alternative to in-feed antibiotics in animal production. However, the effectiveness of the antimicrobial is comprised by its fast absorption in the upper gastrointestinal tract. In this work, two glucoconjugates, thymol α-d-glucopyranoside (TαG) and thymol β-d-glucopyranoside (TβG), were compared with free thymol for their potential to deliver higher concentrations of the active compound to the distal small intestine of supplemented piglets. Additionally, an analytical method was developed and validated for the simultaneous quantification of thymol and its glucoconjugates in different matrices. In stomach contents of pigs fed with 3333 μmol kg
Identifiants
pubmed: 32201813
doi: 10.1021/acsomega.9b04309
pmc: PMC7081444
doi:
Types de publication
Journal Article
Langues
eng
Pagination
5241-5248Informations de copyright
Copyright © 2020 American Chemical Society.
Déclaration de conflit d'intérêts
The authors declare no competing financial interest.
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