Uric acid distribution volume calculated by kinetic modeling and extracellular volume predicted by bioimpedance method.
Dry weight
bioimpedance analysis
dialysis
extracellular fluid
hypotension
Journal
The International journal of artificial organs
ISSN: 1724-6040
Titre abrégé: Int J Artif Organs
Pays: United States
ID NLM: 7802649
Informations de publication
Date de publication:
23 Mar 2020
23 Mar 2020
Historique:
entrez:
24
3
2020
pubmed:
24
3
2020
medline:
24
3
2020
Statut:
aheadofprint
Résumé
Several reports indicate that extracellular volume predicted by bioimpedance analysis method is associated with hydration status of hemodialysis patients. Fundamentally, uric acid does not cross cell membranes by simple diffusion, either by facilitated diffusion or by active transport. In addition, uric acid cannot move through cell membranes in most tissues other than those involved in uric acid excretion. These facts support the interpretation that uric acid distribution volume would therefore correlate with extracellular volume. We examined correlation between uric acid distribution volume calculated by uric acid mass-balance modeling from regular blood test results and extracellular volume predicted by bioimpedance analysis predicted by BCM (Fresenius Medical Care) in 53 patients. There was a significant correlation between uric acid distribution volume ( Uric acid distribution volume calculated by uric acid mass-balance modeling from regular blood test results may be an alternative marker of extracellular volume predicted by bioimpedance analysis.
Sections du résumé
BACKGROUND
BACKGROUND
Several reports indicate that extracellular volume predicted by bioimpedance analysis method is associated with hydration status of hemodialysis patients.
THEORY
BACKGROUND
Fundamentally, uric acid does not cross cell membranes by simple diffusion, either by facilitated diffusion or by active transport. In addition, uric acid cannot move through cell membranes in most tissues other than those involved in uric acid excretion. These facts support the interpretation that uric acid distribution volume would therefore correlate with extracellular volume.
METHODS
METHODS
We examined correlation between uric acid distribution volume calculated by uric acid mass-balance modeling from regular blood test results and extracellular volume predicted by bioimpedance analysis predicted by BCM (Fresenius Medical Care) in 53 patients.
RESULTS
RESULTS
There was a significant correlation between uric acid distribution volume (
CONCLUSION
CONCLUSIONS
Uric acid distribution volume calculated by uric acid mass-balance modeling from regular blood test results may be an alternative marker of extracellular volume predicted by bioimpedance analysis.
Identifiants
pubmed: 32202446
doi: 10.1177/0391398820909835
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM