Some sulfonamides as aldose reductase inhibitors: therapeutic approach in diabetes.

Aldehyde Reductase Animals Diabetes Mellitus / drug therapy Enzyme Inhibitors / chemistry Kidney Sheep Sulfonamides / pharmacology
Enzyme purification aldose reductase enzyme inhibition oxidative stress sulfonamides

Journal

Archives of physiology and biochemistry
ISSN: 1744-4160
Titre abrégé: Arch Physiol Biochem
Pays: England
ID NLM: 9510153

Informations de publication

Date de publication:
Aug 2022
Historique:
pubmed: 24 3 2020
medline: 4 8 2022
entrez: 24 3 2020
Statut: ppublish

Résumé

In this study, aldose reductase (AR) was purified from sheep kidney using chromatographic methods and examined the interactions between some sulfonamides and the enzyme. According to results, sulfonamides display effective inhibitor features for sheep kidney AR with IC

Identifiants

DOI: 10.1080/13813455.2020.1742166 PMID: 32202954
pubmed: 32202954
doi: 10.1080/13813455.2020.1742166
doi:

Substances chimiques

Enzyme Inhibitors 0
Sulfonamides 0
Aldehyde Reductase EC 1.1.1.21

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

979-984

Auteurs

Yeliz Demir (Y)

Department of Pharmacy Services, Nihat Delibalta Göle Vocational High School, Ardahan University, Ardahan, Turkey.

Zeynep Köksal (Z)

Department of Chemistry, Faculty of Engineering and Natural Sciences, Istanbul Medeniyet University, Istanbul, Turkey.

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Classifications MeSH

questionsmedicales.fr › Enzymes et coenzymes › Enzymes › Oxidoreductases › Alcohol oxidoreductases › NAD (+) and NADP (+) dependent Alcohol oxidoreductases › Aldo-keto reductases › Aldose reductase › Some sulfonamides as aldose reductase...
questionsmedicales.fr › Eucaryotes › Animaux › Some sulfonamides as aldose reductase...
questionsmedicales.fr › Maladies endocriniennes › Diabète › Some sulfonamides as aldose reductase...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Antienzymes › Some sulfonamides as aldose reductase...
questionsmedicales.fr › Appareil urogénital › Voies urinaires › Rein › Some sulfonamides as aldose reductase...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Artiodactyla › Ruminants › Ovis › Some sulfonamides as aldose reductase...
questionsmedicales.fr › Composés chimiques organiques › Composés du soufre › Sulfones › Sulfonamides › Some sulfonamides as aldose reductase...