Targeting the Inositol Pyrophosphate Biosynthetic Enzymes in Metabolic Diseases.
5-IP7
IP6
IP6K
NAFL
diabetes
obesity
Journal
Molecules (Basel, Switzerland)
ISSN: 1420-3049
Titre abrégé: Molecules
Pays: Switzerland
ID NLM: 100964009
Informations de publication
Date de publication:
19 Mar 2020
19 Mar 2020
Historique:
received:
20
02
2020
revised:
09
03
2020
accepted:
11
03
2020
entrez:
25
3
2020
pubmed:
25
3
2020
medline:
11
11
2020
Statut:
epublish
Résumé
In mammals, a family of three inositol hexakisphosphate kinases (IP6Ks) synthesizes the inositol pyrophosphate 5-IP7 from IP6. Genetic deletion of
Identifiants
pubmed: 32204420
pii: molecules25061403
doi: 10.3390/molecules25061403
pmc: PMC7144392
pii:
doi:
Substances chimiques
Enzyme Inhibitors
0
Inositol Phosphates
0
inositol heptakisphosphate
0
Phytic Acid
7IGF0S7R8I
Phosphotransferases (Phosphate Group Acceptor)
EC 2.7.4.-
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Subventions
Organisme : NIDDK NIH HHS
ID : R01DK103746
Pays : United States
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