Rapid viral diagnosis and ambulatory management of suspected COVID-19 cases presenting at the infectious diseases referral hospital in Marseille, France, - January 31st to March 1st, 2020: A respiratory virus snapshot.
Adolescent
Adult
Aged
Aged, 80 and over
Betacoronavirus
COVID-19
COVID-19 Testing
Child
Child, Preschool
Clinical Laboratory Techniques
Coronavirus Infections
/ diagnosis
Diagnosis, Differential
Female
France
/ epidemiology
Humans
Infant
Male
Middle Aged
Nasopharynx
/ virology
Pandemics
Pneumonia, Viral
/ diagnosis
Referral and Consultation
SARS-CoV-2
Sputum
/ virology
Young Adult
COVID-19
Coronaviruses
Epidemic
Influenza
SARS-CoV-2
Travel
Journal
Travel medicine and infectious disease
ISSN: 1873-0442
Titre abrégé: Travel Med Infect Dis
Pays: Netherlands
ID NLM: 101230758
Informations de publication
Date de publication:
Historique:
received:
08
03
2020
revised:
12
03
2020
accepted:
14
03
2020
pubmed:
25
3
2020
medline:
25
9
2020
entrez:
25
3
2020
Statut:
ppublish
Résumé
Rapid virological diagnosis is needed to limit the length of isolation for suspected COVID-19 cases. We managed the first 280 patients suspected to have COVID-19 through a rapid care circuit and virological diagnosis in our infectious disease reference hospital in Marseille, France. Rapid viral detection was performed on sputum and nasopharyngeal samples. Over our study period, no SARS-CoV-2 was detected. Results were obtained within approximately 3 h of the arrival of patient samples at the laboratory. Other viral infections were identified in 49% of the patients, with most common pathogens being influenza A and B viruses, rhinovirus, metapneumovirus and common coronaviruses, notably HKU1 and NL63. Early recognition of COVID-19 is critical to isolate confirmed cases and prevent further transmission. Early rule-out of COVID-19 allows public health containment measures to be adjusted by reducing the time spent in isolation.
Sections du résumé
BACKGROUND
Rapid virological diagnosis is needed to limit the length of isolation for suspected COVID-19 cases.
METHOD
We managed the first 280 patients suspected to have COVID-19 through a rapid care circuit and virological diagnosis in our infectious disease reference hospital in Marseille, France. Rapid viral detection was performed on sputum and nasopharyngeal samples.
RESULTS
Over our study period, no SARS-CoV-2 was detected. Results were obtained within approximately 3 h of the arrival of patient samples at the laboratory. Other viral infections were identified in 49% of the patients, with most common pathogens being influenza A and B viruses, rhinovirus, metapneumovirus and common coronaviruses, notably HKU1 and NL63.
CONCLUSION
Early recognition of COVID-19 is critical to isolate confirmed cases and prevent further transmission. Early rule-out of COVID-19 allows public health containment measures to be adjusted by reducing the time spent in isolation.
Identifiants
pubmed: 32205269
pii: S1477-8939(20)30100-9
doi: 10.1016/j.tmaid.2020.101632
pmc: PMC7102626
pii:
doi:
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
101632Commentaires et corrections
Type : CommentIn
Type : CommentIn
Informations de copyright
Copyright © 2020 Elsevier Ltd. All rights reserved.
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