Flow rate variance of a fully implantable pump for the delivery of intravenous treprostinil in pulmonary arterial hypertension.

implantable infusion pump prostanoid pulmonary hypertension treatment

Journal

Pulmonary circulation
ISSN: 2045-8932
Titre abrégé: Pulm Circ
Pays: United States
ID NLM: 101557243

Informations de publication

Date de publication:
Historique:
received: 15 09 2019
accepted: 07 02 2020
entrez: 25 3 2020
pubmed: 25 3 2020
medline: 25 3 2020
Statut: epublish

Résumé

Implantable infusion pumps might improve the convenience and safety of intravenous treprostinil for pulmonary arterial hypertension. The LENUS Pro® pump (approved in Europe) has a fixed flow rate. Based on 126 pumps and 2853 refills, we retrospectively analyzed the actual flow rate from 09/2010 to 09/2018. A relevant flow rate variance is evident after three years; therefore, flow rate monitoring and dose adjustment are mandatory.

Identifiants

pubmed: 32206306
doi: 10.1177/2045894020910136
pii: 10.1177_2045894020910136
pmc: PMC7074510
doi:

Types de publication

Journal Article

Langues

eng

Pagination

2045894020910136

Informations de copyright

© The Author(s) 2020.

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Auteurs

Manuel J Richter (MJ)

Department of Pneumology, Kerckhoff Heart, Rheuma and Thoracic Center, Bad Nauheim, Germany.
Department of Internal Medicine, Justus Liebig University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany.
German Center for Lung Research (DZL), Giessen, Germany.

Satenik Harutyunova (S)

Center for Pulmonary Hypertension, Thorax Clinic at the University Hospital Heidelberg, Heidelberg, Germany.

Tom Bollmann (T)

Department of Internal Medicine, Ernst-Moritz-Arndt University, Greifswald, Germany.

Simon Classen (S)

Department of Vascular Surgery, Kerckhoff Heart, Rheuma and Thoracic Center, Bad Nauheim, Germany.

Jan Fuge (J)

German Center for Lung Research (DZL), Giessen, Germany.
Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.

Henning Gall (H)

Department of Internal Medicine, Justus Liebig University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany.
German Center for Lung Research (DZL), Giessen, Germany.

Felix Gerhardt (F)

Department III of Internal Medicine and Cologne Cardiovascular Research Center (CCRC), Cologne University Heart Center, Cologne, Germany.

Hossein A Ghofrani (HA)

Department of Pneumology, Kerckhoff Heart, Rheuma and Thoracic Center, Bad Nauheim, Germany.
Department of Internal Medicine, Justus Liebig University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany.
German Center for Lung Research (DZL), Giessen, Germany.
Department of Medicine, Imperial College London, London, UK.

Hartmut Gunkel (H)

pro-samed GmbH, Berlin, Germany.

Ekkehard Grünig (E)

Center for Pulmonary Hypertension, Thorax Clinic at the University Hospital Heidelberg, Heidelberg, Germany.

Michael Halank (M)

Department of Internal Medicine I, University Hospital Carl Gustav Carus, Dresden, Germany.

Alexander Heine (A)

Department of Internal Medicine, Ernst-Moritz-Arndt University, Greifswald, Germany.

Hans Klose (H)

Department of Pneumology, University of Hamburg, Hamburg, Germany.

Tobias J Lange (TJ)

Department of Internal Medicine II, Division of Pneumology, University Medical Center Regensburg, Regensburg, Germany.

Claus Neurohr (C)

Department for Pneumology and Respiratory Medicine, Robert-Bosch-Hospital, Gerlingen, Germany.

Kai Nickolaus (K)

Department of Pneumology, Kerckhoff Heart, Rheuma and Thoracic Center, Bad Nauheim, Germany.

Christian F Opitz (CF)

Department of Cardiology, DRK Kliniken Berlin, Berlin, Germany.

Stephan Rosenkranz (S)

Department III of Internal Medicine and Cologne Cardiovascular Research Center (CCRC), Cologne University Heart Center, Cologne, Germany.

Hans-Jürgen Seyfarth (HJ)

Department of Pneumology, University of Leipzig, Leipzig, Germany.

Khodr Tello (K)

Department of Internal Medicine, Justus Liebig University Giessen, Universities of Giessen and Marburg Lung Center (UGMLC), Giessen, Germany.
German Center for Lung Research (DZL), Giessen, Germany.

Ralf Ewert (R)

Department of Internal Medicine, Ernst-Moritz-Arndt University, Greifswald, Germany.

Karen M Olsson (KM)

German Center for Lung Research (DZL), Giessen, Germany.
Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany.

Classifications MeSH