Comorbidity of HIV, hypertension, and diabetes and associated factors among people receiving antiretroviral therapy in Bahir Dar city, Ethiopia.
HIV
Noncommunicable diseases
comorbidity
diabetes mellitus
ethiopia
hypertension
Journal
Journal of comorbidity
ISSN: 2235-042X
Titre abrégé: J Comorb
Pays: England
ID NLM: 101693146
Informations de publication
Date de publication:
Historique:
received:
25
05
2019
accepted:
10
12
2019
entrez:
25
3
2020
pubmed:
25
3
2020
medline:
25
3
2020
Statut:
epublish
Résumé
People living with human immunodeficiency virus (HIV) are facing an increased burden of noncommunicable diseases (NCDs) comorbidity. There is, however, paucity of information on the magnitude of HIV-NCDs comorbidity, its associated factors, and how the health system is responding to the double burden in Ethiopia. To determine the magnitude of comorbidity between HIV and hypertension or diabetes and associated factors among HIV-positive adults receiving antiretroviral therapy (ART) in Bahir Dar city, Ethiopia. A facility-based cross-sectional study was conducted among 560 randomly selected HIV-positive adults taking ART. Data were collected using a structured questionnaire and analyzed using SPSS version 23. Descriptive statistics were used to describe the data. A logistic regression model was fit to identify associated factors with comorbidity of HIV and NCDs. The magnitude of comorbidity was 19.6% (95% confidence interval (CI): 16.0-23.0). Being older (55 and above years) adjusted odds ratio (AOR: 8.5; 95% CI: 3.2-15.1), taking second-line ART regimen containing tenofovir (AOR: 2.7; 95% CI: 1.3-5.6), and increased body mass index (BMI) ≥25 (AOR: 2.7; 95% CI: 1.2-6.5) were the factors associated with comorbidity. Participants reported that they were not managed in an integrated and coordinated manner. The magnitude of comorbidity among adults was high in the study area. Being older, second-line ART regimen and high BMI ≥25 increased the odds of having NCDs among HIV-positive adults. Targeted screening for the incidences of NCDs, addressing modifiable risk factors, and providing integrated care would help to improve the quality of life comorbid patients.
Sections du résumé
BACKGROUND
BACKGROUND
People living with human immunodeficiency virus (HIV) are facing an increased burden of noncommunicable diseases (NCDs) comorbidity. There is, however, paucity of information on the magnitude of HIV-NCDs comorbidity, its associated factors, and how the health system is responding to the double burden in Ethiopia.
OBJECTIVE
OBJECTIVE
To determine the magnitude of comorbidity between HIV and hypertension or diabetes and associated factors among HIV-positive adults receiving antiretroviral therapy (ART) in Bahir Dar city, Ethiopia.
METHODS
METHODS
A facility-based cross-sectional study was conducted among 560 randomly selected HIV-positive adults taking ART. Data were collected using a structured questionnaire and analyzed using SPSS version 23. Descriptive statistics were used to describe the data. A logistic regression model was fit to identify associated factors with comorbidity of HIV and NCDs.
RESULTS
RESULTS
The magnitude of comorbidity was 19.6% (95% confidence interval (CI): 16.0-23.0). Being older (55 and above years) adjusted odds ratio (AOR: 8.5; 95% CI: 3.2-15.1), taking second-line ART regimen containing tenofovir (AOR: 2.7; 95% CI: 1.3-5.6), and increased body mass index (BMI) ≥25 (AOR: 2.7; 95% CI: 1.2-6.5) were the factors associated with comorbidity. Participants reported that they were not managed in an integrated and coordinated manner.
CONCLUSIONS
CONCLUSIONS
The magnitude of comorbidity among adults was high in the study area. Being older, second-line ART regimen and high BMI ≥25 increased the odds of having NCDs among HIV-positive adults. Targeted screening for the incidences of NCDs, addressing modifiable risk factors, and providing integrated care would help to improve the quality of life comorbid patients.
Identifiants
pubmed: 32206632
doi: 10.1177/2235042X19899319
pii: 10.1177_2235042X19899319
pmc: PMC7076577
doi:
Types de publication
Journal Article
Langues
eng
Pagination
2235042X19899319Informations de copyright
© The Author(s) 2020.
Déclaration de conflit d'intérêts
Declaration of conflicting interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Références
PLoS One. 2015 Oct 05;10(10):e0139024
pubmed: 26436759
AIDS. 2012 Jul 31;26 Suppl 1:S1-5
pubmed: 22713477
J Am Soc Hypertens. 2017 Aug;11(8):530-540
pubmed: 28689734
BMC Res Notes. 2016 Aug 02;9:379
pubmed: 27484005
BMC Infect Dis. 2019 Apr 27;19(1):348
pubmed: 31029087
J Glob Health. 2017 Jun;7(1):010414
pubmed: 28685036
HIV Med. 2006 Jan;7(1):10-5
pubmed: 16313287
BMC Public Health. 2014 Feb 13;14:161
pubmed: 24524286
PLoS One. 2018 Dec 31;13(12):e0208635
pubmed: 30596667
J Acquir Immune Defic Syndr. 2014 Sep 1;67 Suppl 1:S68-78
pubmed: 25117962
Int J Qual Health Care. 2016 Dec 1;28(6):802-807
pubmed: 27655788
PLoS One. 2012;7(8):e42624
pubmed: 22952600
BMC Med. 2014 Jul 29;12:125
pubmed: 25070128
J Acquir Immune Defic Syndr. 2014 Sep 1;67 Suppl 1:S40-53
pubmed: 25117960
HIV AIDS (Auckl). 2018 Oct 11;10:181-192
pubmed: 30349400
PLoS One. 2017 Nov 9;12(11):e0187591
pubmed: 29121661
Am J Trop Med Hyg. 2016 Jun 1;94(6):1189-92
pubmed: 26880777
J Acquir Immune Defic Syndr. 2014 Sep 1;67 Suppl 1:S8-16
pubmed: 25117964
BMC Infect Dis. 2015 Jan 17;15:20
pubmed: 25595711
J Acquir Immune Defic Syndr. 2014 Sep 1;67 Suppl 1:S2-7
pubmed: 25117958
Int Arch Med. 2011 Jan 12;4(1):2
pubmed: 21226931
AIDS Res Ther. 2015 Nov 11;12:36
pubmed: 26566389
PLoS One. 2012;7(9):e44575
pubmed: 22984529
AIDS. 2007 Aug 20;21(13):1739-45
pubmed: 17690572
Hypertension. 2018 Jul;72(1):44-55
pubmed: 29776989
Bull World Health Organ. 2019 Jan 1;97(1):10-23
pubmed: 30618461
Public Health Rev. 2015 Dec 9;36:14
pubmed: 29450042
Eur Heart J. 2014 Jun 1;35(21):1373-81
pubmed: 24408888
Arch Intern Med. 2005 May 23;165(10):1179-84
pubmed: 15911733
Int Health. 2015 Nov;7(6):390-9
pubmed: 26103981
J Int AIDS Soc. 2019 Jan;22(1):e25236
pubmed: 30697944
BMJ Open. 2016 Aug 18;6(8):e011175
pubmed: 27540099
AIDS. 2018 Jul 1;32 Suppl 1:S5-S20
pubmed: 29952786
J Hum Hypertens. 2016 Jun;30(6):355-62
pubmed: 26446389
Int J Epidemiol. 2013 Dec;42(6):1754-71
pubmed: 24415610
PLoS Med. 2018 Mar 7;15(3):e1002523
pubmed: 29513674
Braz J Infect Dis. 2013 Jul-Aug;17(4):464-79
pubmed: 23711587
Lancet. 2014 Aug 2;384(9941):384-5
pubmed: 24797574
Health Policy Plan. 2011 Jan;26(1):43-52
pubmed: 20439347
Global Health. 2009 Sep 14;5:9
pubmed: 19751503
J Acquir Immune Defic Syndr. 2014 Sep 1;67 Suppl 1:S99-103
pubmed: 25117967