Impact of Disability, Psychological Status, and Comorbidity on Health-Related Quality of Life Perceived by Subjects with Obesity.


Journal

Obesity facts
ISSN: 1662-4033
Titre abrégé: Obes Facts
Pays: Switzerland
ID NLM: 101469429

Informations de publication

Date de publication:
2020
Historique:
received: 19 08 2019
accepted: 21 01 2020
pubmed: 26 3 2020
medline: 29 9 2020
entrez: 26 3 2020
Statut: ppublish

Résumé

Obesity is a rapidly growing public health problem affecting an increasing number of countries worldwide and creating substantial financial and health burdens. Obesity has a negative impact on health-related quality of life (HRQoL) with reference to physical and mental health status, social relationships, and economic factors. The aim of the present study is to investigate the association of number of comorbidities, psychological status, and disability level with HRQoL in a sample of subjects with obesity. A total of 273 subjects with obesity (199 women and 74 men) were recruited. Medical history and anthropometric measurements were carried out. The Italian version of the Laval questionnaire, the TSD-OC (SIO test for obesity-related disabilities), and SCL-90 (Symptom Checklist-90) tests were administered. The association between HRQoL (global and different domains scores of the Laval questionnaire - dependent variable) and age, body mass index (BMI), comorbidity, TSD-OC, and SCL-90 was analysed using a stepwise linear regression model. BMI, disability (TSD-OC global score), and psychological symptoms (SCL-90 global severity index) were found to be the main determinants of HRQoL. Single domains of HRQoL (symptoms, activity/mobility, personal hygiene/clothing, emotions, social interaction, and sexual life) showed different patterns of associations with each domain of the Laval questionnaire. BMI, pain, and social life disruptions were found to be significantly associated with most of the HRQoL domains while age, comorbidities, psychological problems (depression, interpersonal symptoms, somatization), and disability were associated with only some domains of the Laval questionnaire. Education, psychological symptoms (obsessive-compulsive, anxiety, hostility, phobic anxiety, paranoid ideation), and disability domains (stiffness, housework, outdoor activities, occupational activities) were not associated with any of the dimensions of the Laval questionnaire. The present study identified key determinants of QoL in subjects with obesity, which could help in refining the multidimensional diagnostic assessment of obesity as well as designing more effective interventions to improve HRQoL in these patients.

Identifiants

pubmed: 32208387
pii: 000506079
doi: 10.1159/000506079
pmc: PMC7250341
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

191-200

Informations de copyright

© 2020 The Author(s) Published by S. Karger AG, Basel.

Références

PLoS One. 2013 Oct 11;8(10):e75491
pubmed: 24146756
Health Qual Life Outcomes. 2011 Aug 15;9:66
pubmed: 21843326
Disabil Rehabil. 2011;33(25-26):2509-18
pubmed: 21542694
Qual Life Res. 2004 Mar;13(2):299-310
pubmed: 15085902
Nutrients. 2016 Nov 25;8(12):
pubmed: 27897994
Int J Obes Relat Metab Disord. 2003 Oct;27(10):1227-32
pubmed: 14513071
J Public Health (Oxf). 2005 Jun;27(2):156-64
pubmed: 15820993
Int J Endocrinol. 2014;2014:847871
pubmed: 24707290
Clin Obes. 2017 Oct;7(5):273-289
pubmed: 28695722
Health Qual Life Outcomes. 2017 May 15;15(1):101
pubmed: 28506319
Clin Geriatr Med. 2005 Nov;21(4):677-87, v
pubmed: 16182081
Obesity (Silver Spring). 2014 May;22(5):1367-72
pubmed: 24415405
Obes Rev. 2008 May;9(3):204-18
pubmed: 18331422
Soc Sci Med. 1995 Nov;41(10):1403-9
pubmed: 8560308
Obes Rev. 2001 Aug;2(3):173-82
pubmed: 12120102

Auteurs

Lorenzo Maria Donini (LM)

Medical Pathophysiology, Food Science and Endocrinology Section, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy, lorenzomaria.donini@uniroma1.it.

Aldo Rosano (A)

Italian National Agency for Regional Healthcare Services (AGENAS), Rome, Italy.

Luca Di Lazzaro (L)

Medical Pathophysiology, Food Science and Endocrinology Section, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.

Carla Lubrano (C)

Medical Pathophysiology, Food Science and Endocrinology Section, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.

Mariagrazia Carbonelli (M)

San Camillo-Forlanini Hospital, Rome, Italy.

Alessandro Pinto (A)

Medical Pathophysiology, Food Science and Endocrinology Section, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.

Anna Maria Giusti (AM)

Medical Pathophysiology, Food Science and Endocrinology Section, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.

Andrea Lenzi (A)

Medical Pathophysiology, Food Science and Endocrinology Section, Department of Experimental Medicine, Sapienza University of Rome, Rome, Italy.

Mario Siervo (M)

Division of Physiology, Pharmacology and Neuroscience, School of Life Sciences, University of Nottingham, Nottingham, United Kingdom.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH