High-Resolution Shortwave Infrared Imaging of Vascular Disorders Using Gold Nanoclusters.

Monte Carlo restoration imaging processing bone morphogenetic protein 9 (Bmp9) gold nanoclusters shortwave infrared fluorescence vascular disorder

Journal

ACS nano
ISSN: 1936-086X
Titre abrégé: ACS Nano
Pays: United States
ID NLM: 101313589

Informations de publication

Date de publication:
28 04 2020
Historique:
pubmed: 27 3 2020
medline: 15 5 2021
entrez: 27 3 2020
Statut: ppublish

Résumé

We synthesized a generation of water-soluble, atomically precise gold nanoclusters (Au NCs) with anisotropic surface containing a short dithiol pegylated chain (AuMHA/TDT). The AuMHA/TDT exhibit a high brightness (QY ∼ 6%) in the shortwave infrared (SWIR) spectrum with a detection above 1250 nm. Furthermore, they show an extended half-life in blood (

Identifiants

pubmed: 32208639
doi: 10.1021/acsnano.0c01174
doi:

Substances chimiques

Water 059QF0KO0R
Gold 7440-57-5

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

4973-4981

Auteurs

Zhixi Yu (Z)

Cancer Targets and Experimental Therapeutics, Institute for Advanced Biosciences (IAB), University of Grenoble Alpes (UGA)/ INSERM-U1209/CNRS-UMR 5309, 38700 Grenoble, France.

Benjamin Musnier (B)

Cancer Targets and Experimental Therapeutics, Institute for Advanced Biosciences (IAB), University of Grenoble Alpes (UGA)/ INSERM-U1209/CNRS-UMR 5309, 38700 Grenoble, France.

K David Wegner (KD)

BAM Federal Institute for Materials Research and Testing, Richard-Willstaetter-Str. 11, 12489 Berlin, Germany.

Maxime Henry (M)

Cancer Targets and Experimental Therapeutics, Institute for Advanced Biosciences (IAB), University of Grenoble Alpes (UGA)/ INSERM-U1209/CNRS-UMR 5309, 38700 Grenoble, France.

Benoit Chovelon (B)

Institut de Biologie et Pathologie, Centre Hospitalier Universitaire (CHU) de Grenoble Alpes, 38700 Grenoble, France.

Agnès Desroches-Castan (A)

Biology of Cancer and Infection Laboratory, University Grenoble Alpes, INSERM, CEA, 38000 Grenoble, France.

Arnold Fertin (A)

TIMC-IMAG Laboratory, University of Grenoble Alpes, CNRS-UMR 5525, 38700 Grenoble, France.

Ute Resch-Genger (U)

BAM Federal Institute for Materials Research and Testing, Richard-Willstaetter-Str. 11, 12489 Berlin, Germany.

Sabine Bailly (S)

Biology of Cancer and Infection Laboratory, University Grenoble Alpes, INSERM, CEA, 38000 Grenoble, France.

Jean-Luc Coll (JL)

Cancer Targets and Experimental Therapeutics, Institute for Advanced Biosciences (IAB), University of Grenoble Alpes (UGA)/ INSERM-U1209/CNRS-UMR 5309, 38700 Grenoble, France.

Yves Usson (Y)

TIMC-IMAG Laboratory, University of Grenoble Alpes, CNRS-UMR 5525, 38700 Grenoble, France.

Véronique Josserand (V)

Cancer Targets and Experimental Therapeutics, Institute for Advanced Biosciences (IAB), University of Grenoble Alpes (UGA)/ INSERM-U1209/CNRS-UMR 5309, 38700 Grenoble, France.

Xavier Le Guével (X)

Cancer Targets and Experimental Therapeutics, Institute for Advanced Biosciences (IAB), University of Grenoble Alpes (UGA)/ INSERM-U1209/CNRS-UMR 5309, 38700 Grenoble, France.

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Classifications MeSH