Identification of a common conserved neutralizing linear B-cell epitope in the VP3 protein of waterfowl parvoviruses.


Journal

Avian pathology : journal of the W.V.P.A
ISSN: 1465-3338
Titre abrégé: Avian Pathol
Pays: England
ID NLM: 8210638

Informations de publication

Date de publication:
Aug 2020
Historique:
pubmed: 27 3 2020
medline: 16 3 2021
entrez: 27 3 2020
Statut: ppublish

Résumé

Waterfowl parvoviruses (WPVs) including goose parvovirus (GPV), novel GPV-related virus (NGPV) and Muscovy duck parvovirus (MDPV) cause significant economic losses and epizootic threat to the waterfowl industries, and little is known about the B-cell epitopes of WPVs. In this study, a monoclonal antibody (mAb) 5B5 against the VP3 protein of NGPV was used to identify the possible epitope in the three kinds of WPVs. The mAb 5B5 had neutralizing activities to the three viruses, and reacted with the conserved linear B-cell epitopes of

Identifiants

pubmed: 32208867
doi: 10.1080/03079457.2020.1746743
doi:

Substances chimiques

Antibodies, Monoclonal 0
Epitopes, B-Lymphocyte 0
Viral Proteins 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

325-334

Auteurs

Caiyu Lian (C)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian, People's Republic of China.
Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian, People's Republic of China.
Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian, People's Republic of China.

Ruihua Zhang (R)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian, People's Republic of China.
Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian, People's Republic of China.
Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian, People's Republic of China.

Jingjing Lan (J)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian, People's Republic of China.
Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian, People's Republic of China.
Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian, People's Republic of China.

Yupeng Yang (Y)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian, People's Republic of China.
Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian, People's Republic of China.

Hanqing Li (H)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian, People's Republic of China.
Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian, People's Republic of China.

Nana Sui (N)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian, People's Republic of China.
Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian, People's Republic of China.
Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian, People's Republic of China.

Zhijing Xie (Z)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian, People's Republic of China.
Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian, People's Republic of China.
Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian, People's Republic of China.

Shijin Jiang (S)

Department of Preventive Veterinary Medicine, College of Veterinary Medicine, Shandong Agricultural University, Taian, People's Republic of China.
Shandong Provincial Key Laboratory of Animal Biotechnology and Disease Control and Prevention, Taian, People's Republic of China.
Shandong Provincial Engineering Technology Research Center of Animal Disease Control and Prevention, Taian, People's Republic of China.

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