Aortic Aneurysms and Dissections Series: Part II: Dynamic Signaling Responses in Aortic Aneurysms and Dissections.
angiotensin II receptor
aorta
aortic aneurysms
signal transduction pathways
transforming growth factor
Journal
Arteriosclerosis, thrombosis, and vascular biology
ISSN: 1524-4636
Titre abrégé: Arterioscler Thromb Vasc Biol
Pays: United States
ID NLM: 9505803
Informations de publication
Date de publication:
04 2020
04 2020
Historique:
entrez:
27
3
2020
pubmed:
27
3
2020
medline:
14
7
2020
Statut:
ppublish
Résumé
Aortic structure and function are controlled by the coordinated actions of different aortic cells and the extracellular matrix. Several pathways have been identified that control the aortic wall in a cell-type-specific manner and play diverse roles in various phases of aortic injury, repair, and remodeling. This complexity of signaling in the aortic wall poses challenges to the development of therapeutic strategies for treating aortic aneurysms and dissections. Here, in part II of this Recent Highlights series on aortic aneurysms and dissections, we will summarize recent studies published in
Identifiants
pubmed: 32208998
doi: 10.1161/ATVBAHA.120.313804
pmc: PMC7122036
mid: NIHMS1566227
doi:
Substances chimiques
Receptors, Angiotensin
0
Transforming Growth Factor beta
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
e78-e86Subventions
Organisme : NHLBI NIH HHS
ID : R01 HL133723
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL143359
Pays : United States
Organisme : NIGMS NIH HHS
ID : P30 GM127211
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL127111
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL131980
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL139748
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL134731
Pays : United States
Organisme : NHLBI NIH HHS
ID : R01 HL107326
Pays : United States
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