Antibacterial activity of betle leaf (Piper betle l.) extract on inhibiting Staphylococcus aureus in conjunctivitis patient.
Piper betle L. leaf extract
Staphylococcus aureus
bacterial conjungtivitis
Journal
American journal of clinical and experimental immunology
ISSN: 2164-7712
Titre abrégé: Am J Clin Exp Immunol
Pays: United States
ID NLM: 101587157
Informations de publication
Date de publication:
2020
2020
Historique:
received:
26
11
2019
accepted:
30
12
2019
entrez:
27
3
2020
pubmed:
27
3
2020
medline:
27
3
2020
Statut:
epublish
Résumé
The aim of this study is to determine the antibacterial activity of Piper betle L. leaf extract on inhibiting Staphylococcus aureus in conjunctivitis patient. This study follows a post-test only group experimental design. Antibacterial activities of five Piper betle L. extract concentrations (0.5%, 1%, 1.5%, 2%, 2.5%, and 3%) against Staphylococcus aureus were evaluated by agar well diffusion method. The negative control group (P-) was treated with standard 10% DMSO solution, the positive control group (P+) with ceftriaxone. The diameters of clear zone surrounding the well were analyzed with Kruskal-Wallis test and showed that in between 1% and 1.5%; 1.5% and 2%; 2% and 2.5%; 2.5% and 3% concentrations do not show a significant difference but in between 0.5% and 1%; 0.5% and 1.5%; 0.5% and 2%; 0.5% and 2.5%; 0.5% and 3%; 1% and 2%; 1% and 2.5%; 1% and 3%; 1.5% and 2.5%; 1.5% and 3%; 2% and 3% concentrations, Piper betle L. leaf extract shows a significant difference on inhibiting the growth of Staphylococcus aureus. In conclusion the results obtained show that that Piper betle L. leaf extract has a significant potential use as an antibacterial agent.
Types de publication
Journal Article
Langues
eng
Pagination
1-5Informations de copyright
AJCEI Copyright © 2020.
Déclaration de conflit d'intérêts
None.
Références
Recent Pat Inflamm Allergy Drug Discov. 2018;12(2):120-127
pubmed: 29380707
Evid Based Complement Alternat Med. 2008 Mar;5(1):95-101
pubmed: 18317555
Curr Med Chem. 2015;22(1):132-49
pubmed: 25245513
Evid Based Complement Alternat Med. 2009 Sep;6(3):351-6
pubmed: 18955257
J Trauma. 2009 Jan;66(1):82-90; discussion 90-1
pubmed: 19131809
Crit Care. 2015 Jun 12;19:243
pubmed: 26067660
Clin Microbiol Rev. 1999 Oct;12(4):564-82
pubmed: 10515903
J Antimicrob Chemother. 2001 Oct;48(4):487-91
pubmed: 11581226
Acad Emerg Med. 2007 Jan;14(1):1-5
pubmed: 17119185
Plast Reconstr Surg. 1998 Mar;101(3):756-65
pubmed: 9500394
Biomaterials. 2005 Aug;26(22):4670-6
pubmed: 15722137
Acta Ophthalmol. 2008 Feb;86(1):5-17
pubmed: 17970823
Pak J Biol Sci. 2017;20(2):70-81
pubmed: 29022997
Int J Low Extrem Wounds. 2005 Jun;4(2):88-92
pubmed: 15911921