Management and outcomes following emergency surgery for traumatic brain injury - A multi-centre, international, prospective cohort study (the Global Neurotrauma Outcomes Study).
Brain injuries
Epidemiology
Global health
Injuries
Neurosurgery
Traumatic
Journal
International journal of surgery protocols
ISSN: 2468-3574
Titre abrégé: Int J Surg Protoc
Pays: England
ID NLM: 101758186
Informations de publication
Date de publication:
2020
2020
Historique:
received:
26
01
2020
accepted:
09
02
2020
entrez:
27
3
2020
pubmed:
27
3
2020
medline:
27
3
2020
Statut:
epublish
Résumé
Traumatic brain injury (TBI) accounts for a significant amount of death and disability worldwide and the majority of this burden affects individuals in low-and-middle income countries. Despite this, considerable geographical differences have been reported in the care of TBI patients. On this background, we aim to provide a comprehensive international picture of the epidemiological characteristics, management and outcomes of patients undergoing emergency surgery for traumatic brain injury (TBI) worldwide. The Global Neurotrauma Outcomes Study (GNOS) is a multi-centre, international, prospective observational cohort study. Any unit performing emergency surgery for TBI worldwide will be eligible to participate. All TBI patients who receive emergency surgery in any given consecutive 30-day period beginning between 1st of November 2018 and 31st of December 2019 in a given participating unit will be included. Data will be collected via a secure online platform in anonymised form. The primary outcome measures for the study will be 14-day mortality (or survival to hospital discharge, whichever comes first). Final day of data collection for the primary outcome measure is February 13th. Secondary outcome measures include return to theatre and surgical site infection. This project will not affect clinical practice and has been classified as clinical audit following research ethics review. Access to source data will be made available to collaborators through national or international anonymised datasets on request and after review of the scientific validity of the proposed analysis by the central study team.
Identifiants
pubmed: 32211566
doi: 10.1016/j.isjp.2020.02.001
pii: S2468-3574(20)30004-8
pmc: PMC7082548
doi:
Types de publication
Journal Article
Langues
eng
Pagination
1-7Informations de copyright
© 2020 The Authors.
Déclaration de conflit d'intérêts
The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
Références
J Trauma. 1996 Jul;41(1):120-2
pubmed: 8676403
World Neurosurg. 2018 Apr;112:e240-e254
pubmed: 29325943
Lancet. 2018 Apr 21;391(10130):1589-1598
pubmed: 29306587
J Neurosurg. 2011 Dec;115(6):1262-72
pubmed: 21962030
PLoS One. 2016 Sep 01;11(9):e0161554
pubmed: 27583787
J Neurosurg. 2017 Mar 17;:1-8
pubmed: 28306417
Lancet. 2015 May 30;385(9983):2209-19
pubmed: 25662414
N Engl J Med. 1981 Jun 18;304(25):1511-8
pubmed: 7231489
Lancet Respir Med. 2014 May;2(5):380-6
pubmed: 24740011
J Neurosurg. 1995 Jun;82(6):961-5
pubmed: 7760198
Lancet Neurol. 2019 Jan;18(1):56-87
pubmed: 30497965
Br J Surg. 2016 Jul;103(8):971-988
pubmed: 27145169
Acta Neurochir (Wien). 1988;90(3-4):111-6
pubmed: 3354356
Ann Surg. 2005 Sep;242(3):364-70; discussion 370-4
pubmed: 16135922
World J Surg. 2015 Jun;39(6):1335-40
pubmed: 25860988
Int J Surg. 2014 Dec;12(12):1495-9
pubmed: 25046131
Lancet Infect Dis. 2018 May;18(5):516-525
pubmed: 29452941
J Neurotrauma. 2007;24 Suppl 1:S1-106
pubmed: 17511534
Int J Epidemiol. 2009 Apr;38(2):452-8
pubmed: 18782898