A Simple Pattern of Movement is not Able to Inhibit Experimental Pain in FM Patients and Controls: an sLORETA Study.
chronic pain
laser-evoked potentials
motor activity
Journal
Brain sciences
ISSN: 2076-3425
Titre abrégé: Brain Sci
Pays: Switzerland
ID NLM: 101598646
Informations de publication
Date de publication:
24 03 2020
24 03 2020
Historique:
received:
14
02
2020
revised:
09
03
2020
accepted:
23
03
2020
entrez:
28
3
2020
pubmed:
28
3
2020
medline:
28
3
2020
Statut:
epublish
Résumé
Motor cortex activation seems to induce an analgesic effect on pain that would be different between patients with fibromyalgia (FM) and control subjects. This study was conducted to analyze the changes of the laser-evoked potentials (LEPs) induced during a finger tapping task in the FM patients and the controls employing a multi-dipolar analysis according to Standardized low resolution brain electromagnetic tomography (sLORETA) method. The LEPs from 38 FM patients and 21 controls were analyzed. The LEPs were recorded while subjects performed a slow and a fast finger tapping task. We confirmed that the difference between N1, N2 and P2 wave amplitudes between conditions and groups was not significant. In control subjects, the fast finger tapping task induced a modification of cortical source activation in the main areas processing laser stimulation from the moving hand independently from the movement speed. In summary, a simple and repetitive movement is not able to induce consistent inhibition of experimental pain evoked by the moving and the not moving hand in each group. It could interfere with LEP sources within the limbic area at least in control subjects, without inhibit cortical responses or explain the different pattern of motor and pain interaction in FM patients.
Identifiants
pubmed: 32214053
pii: brainsci10030190
doi: 10.3390/brainsci10030190
pmc: PMC7139913
pii:
doi:
Types de publication
Journal Article
Langues
eng
Déclaration de conflit d'intérêts
The authors have no potential conflict of interest to declare.
Références
Eur J Neurosci. 2007 Mar;25(6):1900-7
pubmed: 17432974
J Rheumatol. 2016 Sep;43(9):1743-8
pubmed: 27370877
Pain Res Treat. 2019 Jan 16;2019:2623161
pubmed: 30792923
Neurophysiol Clin. 2003 Dec;33(6):303-14
pubmed: 14678844
Pain Res Treat. 2013;2013:515730
pubmed: 23365736
Exp Brain Res. 2010 Aug;205(1):1-12
pubmed: 20607220
Pain Pract. 2017 Jan;17(1):25-31
pubmed: 26892176
Arch Rheumatol. 2015 Nov 26;31(2):158-161
pubmed: 29900953
Curr Pain Headache Rep. 2011 Oct;15(5):358-67
pubmed: 21725900
Brain Stimul. 2019 Sep - Oct;12(5):1169-1176
pubmed: 30987860
Neurology. 2006 Nov 14;67(9):1568-74
pubmed: 17101886
Pain. 2011 Jul;152(7):1469-77
pubmed: 21339052
Clin Exp Rheumatol. 2017 May-Jun;35 Suppl 105(3):100-105
pubmed: 28681715
J Headache Pain. 2010 Dec;11(6):505-12
pubmed: 20714776
Cochrane Database Syst Rev. 2018 Mar 16;3:CD008208
pubmed: 29547226
Restor Neurol Neurosci. 2015;33(5):597-609
pubmed: 25777683
PLoS One. 2020 Jan 23;15(1):e0228158
pubmed: 31971993
J Neurol. 2014 Mar;261(3):461-72
pubmed: 24366650
Z Rheumatol. 2019 Nov;78(9):889-893
pubmed: 30324279
Pain. 2010 Sep;150(3):428-38
pubmed: 20494517
Magn Reson Med. 2019 Apr;81(4):2720-2727
pubmed: 30368894
Neuroimage. 2011 Feb 1;54(3):2237-49
pubmed: 20932917
J Physiol. 2017 Jul 1;595(13):4141-4150
pubmed: 28369946
Pain Pract. 2016 Mar;16(3):294-304
pubmed: 25581213
Clin Neurophysiol. 2014 Nov;125(11):2150-2206
pubmed: 25034472
Semin Arthritis Rheum. 2016 Dec;46(3):319-329
pubmed: 27916278
Neuroimage. 2019 Nov 15;202:116051
pubmed: 31351164
Cereb Cortex. 2015 Dec;25(12):4789-98
pubmed: 26250779
Neuropsychologia. 1971 Mar;9(1):97-113
pubmed: 5146491
Pain Physician. 2012 Sep-Oct;15(5):E693-9
pubmed: 22996863
Methods Find Exp Clin Pharmacol. 2002;24 Suppl D:5-12
pubmed: 12575463
Clin Neurophysiol. 2002 May;113(5):702-12
pubmed: 11976050
Cephalalgia. 2018 Jun;38(7):1245-1256
pubmed: 28856913
Brain Res. 2012 Jan 30;1435:105-17
pubmed: 22192409
CNS Neurosci Ther. 2014 Jun;20(6):565-7
pubmed: 24836741